Wolbachia- and Onchocerca volvulus-induced keratitis (River blindness) is dependent on myeloid differentiation factor 88

Illona Gillette-Ferguson; Amy G. Hise; Yan Sun; Eugenia Diaconu; Helen F. McGarry; Mark Taylor; Eric Pearlman

doi:10.1128/iai.74.4.2442-2445.2006

Wolbachia- and Onchocerca volvulus-induced keratitis (River blindness) is dependent on myeloid differentiation factor 88

Illona Gillette-Ferguson, Amy G. Hise, Yan Sun, Eugenia Diaconu, Helen F. McGarry, Mark Taylor, Eric Pearlman

Tropical Disease Biology

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dependent on expression of myeloid differentiation factor 88.

Original language	English
Pages (from-to)	2442-2445
Number of pages	4
Journal	Infection and Immunity
Volume	74
Issue number	4
DOIs	https://doi.org/10.1128/iai.74.4.2442-2445.2006
Publication status	Published - 1 Apr 2006

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10.1128/iai.74.4.2442-2445.2006

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title = "Wolbachia- and Onchocerca volvulus-induced keratitis (River blindness) is dependent on myeloid differentiation factor 88",

abstract = "Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dependent on expression of myeloid differentiation factor 88.",

author = "Illona Gillette-Ferguson and Hise, \{Amy G.\} and Yan Sun and Eugenia Diaconu and McGarry, \{Helen F.\} and Mark Taylor and Eric Pearlman",

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T1 - Wolbachia- and Onchocerca volvulus-induced keratitis (River blindness) is dependent on myeloid differentiation factor 88

AU - Gillette-Ferguson, Illona

AU - Hise, Amy G.

AU - Sun, Yan

AU - Diaconu, Eugenia

AU - McGarry, Helen F.

AU - Taylor, Mark

AU - Pearlman, Eric

PY - 2006/4/1

Y1 - 2006/4/1

N2 - Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dependent on expression of myeloid differentiation factor 88.

AB - Endosymbiotic Wolbachia bacteria that infect the filarial nematode Onchocerca volvulus were previously found to have an essential role in the pathogenesis of river blindness. The current study demonstrates that corneal inflammation induced by Wolbachia or O. volvulus antigens containing Wolbachia is completely dependent on expression of myeloid differentiation factor 88.

U2 - 10.1128/iai.74.4.2442-2445.2006

DO - 10.1128/iai.74.4.2442-2445.2006

M3 - Article

SN - 0019-9567

VL - 74

SP - 2442

EP - 2445

JO - Infection and Immunity

JF - Infection and Immunity

IS - 4

ER -

Wolbachia- and Onchocerca volvulus-induced keratitis (River blindness) is dependent on myeloid differentiation factor 88

Abstract

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