Whole genome sequence analysis of shigella from malawi identifies fluoroquinolone resistance

George E. Stenhouse; Khuzwayo C. Jere; Chikondi Peno; Rebecca J. Bengtsson; End Chinyama; Jonathan Mandolo; Amy Cain; Miren Iturriza-Gómara; Naor Bar-Zeev; Nigel A. Cunliffe; Jennifer Cornick; Kate S. Baker

doi:10.1099/mgen.0.000532

Whole genome sequence analysis of shigella from malawi identifies fluoroquinolone resistance

George E. Stenhouse, Khuzwayo C. Jere, Chikondi Peno, Rebecca J. Bengtsson, End Chinyama, Jonathan Mandolo, Amy Cain, Miren Iturriza-Gómara, Naor Bar-Zeev, Nigel A. Cunliffe, Jennifer Cornick, Kate S. Baker

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.

Original language	English
Article number	000532
Journal	Microbial genomics
Volume	7
Issue number	5
DOIs	https://doi.org/10.1099/mgen.0.000532
Publication status	Published - 1 Jan 2021
Externally published	Yes

Keywords

AMR
FQR
Shigella
WGS

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10.1099/mgen.0.000532Licence: CC BY

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title = "Whole genome sequence analysis of shigella from malawi identifies fluoroquinolone resistance",

abstract = "Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.",

keywords = "AMR, FQR, Shigella, WGS",

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T1 - Whole genome sequence analysis of shigella from malawi identifies fluoroquinolone resistance

AU - Stenhouse, George E.

AU - Jere, Khuzwayo C.

AU - Peno, Chikondi

AU - Bengtsson, Rebecca J.

AU - Chinyama, End

AU - Mandolo, Jonathan

AU - Cain, Amy

AU - Iturriza-Gómara, Miren

AU - Bar-Zeev, Naor

AU - Cunliffe, Nigel A.

AU - Cornick, Jennifer

AU - Baker, Kate S.

PY - 2021/1/1

Y1 - 2021/1/1

N2 - Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.

AB - Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1.

KW - AMR

KW - FQR

KW - Shigella

KW - WGS

U2 - 10.1099/mgen.0.000532

DO - 10.1099/mgen.0.000532

M3 - Article

SN - 2057-5858

VL - 7

JO - Microbial genomics

JF - Microbial genomics

IS - 5

M1 - 000532

ER -

Whole genome sequence analysis of shigella from malawi identifies fluoroquinolone resistance

Abstract

Keywords

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