Venom Evolution: Gene Loss Shapes Phenotypic Adaptation

Nick Casewell

doi:10.1016/j.cub.2016.07.082

Venom Evolution: Gene Loss Shapes Phenotypic Adaptation

Nick Casewell

Tropical Disease Biology

Research output: Contribution to journal › Short survey › peer-review

14 Citations (Scopus)

Abstract

Snake venoms are variable protein mixtures with a multitude of bioactivities. New work shows, surprisingly, that it is the loss of toxin-encoding genes that strongly influences venom function in rattlesnakes, highlighting how gene loss can underpin adaptive phenotypic change.

Original language	English
Pages (from-to)	R849-R851
Journal	Current Biology
Volume	26
Issue number	18
Early online date	26 Sept 2016
DOIs	https://doi.org/10.1016/j.cub.2016.07.082
Publication status	E-pub ahead of print - 26 Sept 2016

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10.1016/j.cub.2016.07.082

Casewell Current Biology DispatchAccepted author manuscript, 261 KB

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title = "Venom Evolution: Gene Loss Shapes Phenotypic Adaptation",

abstract = "Snake venoms are variable protein mixtures with a multitude of bioactivities. New work shows, surprisingly, that it is the loss of toxin-encoding genes that strongly influences venom function in rattlesnakes, highlighting how gene loss can underpin adaptive phenotypic change.",

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AB - Snake venoms are variable protein mixtures with a multitude of bioactivities. New work shows, surprisingly, that it is the loss of toxin-encoding genes that strongly influences venom function in rattlesnakes, highlighting how gene loss can underpin adaptive phenotypic change.

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DO - 10.1016/j.cub.2016.07.082

M3 - Short survey

SN - 0960-9822

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JO - Current Biology

JF - Current Biology

IS - 18

ER -

Venom Evolution: Gene Loss Shapes Phenotypic Adaptation

Abstract

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