Skip to main navigation Skip to search Skip to main content

Using a household-structured branching process to analyse contact tracing in the SARS-CoV-2 pandemic

  • Martyn Fyles
  • , Elizabeth Fearon
  • , Christopher Overton
  • , Tom Wingfield
  • , Graham F. Medley
  • , Ian Hall
  • , Lorenzo Pellis
  • , Thomas House
  • University of Manchester
  • Alan Turing Institute
  • London School of Hygiene and Tropical Medicine
  • Liverpool University Hospitals NHS Foundation Trust
  • Karolinska Institutet
  • UK Health Security Agency
  • Joint UNIversities Pandemic and Epidemiological Research
  • Science and Technology Facilities Council

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

We explore strategies of contact tracing, case isolation and quarantine of exposed contacts to control the SARS-CoV-2 epidemic using a branching process model with household structure. This structure reflects higher transmission risks among household members than among non-household members. We explore strategic implementation choices that make use of household structure, and investigate strategies including two-step tracing, backwards tracing, smartphone tracing and tracing upon symptom report rather than test results. The primary model outcome is the effect of contact tracing, in combination with different levels of physical distancing, on the growth rate of the epidemic. Furthermore, we investigate epidemic extinction times to indicate the time period over which interventions must be sustained. We consider effects of non-uptake of isolation/quarantine, non-adherence, and declining recall of contacts over time. Our results find that, compared to self-isolation of cases without contact tracing, a contact tracing strategy designed to take advantage of household structure allows for some relaxation of physical distancing measures but cannot completely control the epidemic absent of other measures. Even assuming no imported cases and sustainment of moderate physical distancing, testing and tracing efforts, the time to bring the epidemic to extinction could be in the order of months to years.

Original languageEnglish
Article number20200267
Pages (from-to)20200267
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Volume376
Issue number1829
Early online date31 May 2021
DOIs
Publication statusPublished - 19 Jul 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • contact tracing
  • COVID-19
  • epidemic
  • epidemiology
  • infectious disease
  • SARS-CoV-2

Fingerprint

Dive into the research topics of 'Using a household-structured branching process to analyse contact tracing in the SARS-CoV-2 pandemic'. Together they form a unique fingerprint.

Cite this