Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

Lalith P.M. Wijedoru; Varun Kumar; Ngoun Chanpheaktra; Kheng Chheng; Henk L. Smits; Rob Pastoor; Tran Vu Thieu Nga; Stephen Baker; Vanaporn Wuthiekanun; Sharon J. Peacock; Hor Putchhat; Christopher Parry

doi:10.1093/tropej/fmr032

Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

Lalith P.M. Wijedoru
, Varun Kumar
, Ngoun Chanpheaktra
, Kheng Chheng
, Henk L. Smits
, Rob Pastoor
, Tran Vu Thieu Nga
, Stephen Baker
, Vanaporn Wuthiekanun
, Sharon J. Peacock
, Hor Putchhat
, Christopher Parry

International Public Health

Liverpool School of Tropical Medicine
Angkor Hospital for Children
Royal Tropical Institute
University of Oxford
Mahidol University
University of Cambridge

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

Original language	English
Article number	fmr032
Pages (from-to)	68-70
Number of pages	3
Journal	Journal of Tropical Pediatrics
Volume	58
Issue number	1
DOIs	https://doi.org/10.1093/tropej/fmr032
Publication status	Published - 1 Feb 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Blood culture
Children
Nucleic acid amplification test
Rapid diagnostic test
Typhoid fever

Access to Document

10.1093/tropej/fmr032

Cite this

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title = "Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia",

abstract = "Typhoid fever was confirmed by positive blood culture in 5 (3.7\%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 \%) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.",

keywords = "Blood culture, Children, Nucleic acid amplification test, Rapid diagnostic test, Typhoid fever",

author = "Wijedoru, \{Lalith P.M.\} and Varun Kumar and Ngoun Chanpheaktra and Kheng Chheng and Smits, \{Henk L.\} and Rob Pastoor and Nga, \{Tran Vu Thieu\} and Stephen Baker and Vanaporn Wuthiekanun and Peacock, \{Sharon J.\} and Hor Putchhat and Christopher Parry",

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doi = "10.1093/tropej/fmr032",

language = "English",

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T1 - Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

AU - Wijedoru, Lalith P.M.

AU - Kumar, Varun

AU - Chanpheaktra, Ngoun

AU - Chheng, Kheng

AU - Smits, Henk L.

AU - Pastoor, Rob

AU - Nga, Tran Vu Thieu

AU - Baker, Stephen

AU - Wuthiekanun, Vanaporn

AU - Peacock, Sharon J.

AU - Putchhat, Hor

AU - Parry, Christopher

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

AB - Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

KW - Blood culture

KW - Children

KW - Nucleic acid amplification test

KW - Rapid diagnostic test

KW - Typhoid fever

U2 - 10.1093/tropej/fmr032

DO - 10.1093/tropej/fmr032

M3 - Article

SN - 0142-6338

VL - 58

SP - 68

EP - 70

JO - Journal of Tropical Pediatrics

JF - Journal of Tropical Pediatrics

IS - 1

M1 - fmr032

ER -

Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

Abstract

UN SDGs

Keywords

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