Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

Lalith P.M. Wijedoru; Varun Kumar; Ngoun Chanpheaktra; Kheng Chheng; Henk L. Smits; Rob Pastoor; Tran Vu Thieu Nga; Stephen Baker; Vanaporn Wuthiekanun; Sharon J. Peacock; Hor Putchhat; Christopher Parry

doi:10.1093/tropej/fmr032

Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

Lalith P.M. Wijedoru, Varun Kumar, Ngoun Chanpheaktra, Kheng Chheng, Henk L. Smits, Rob Pastoor, Tran Vu Thieu Nga, Stephen Baker, Vanaporn Wuthiekanun, Sharon J. Peacock, Hor Putchhat, Christopher Parry

International Public Health

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

Original language	English
Article number	fmr032
Pages (from-to)	68-70
Number of pages	3
Journal	Journal of Tropical Pediatrics
Volume	58
Issue number	1
DOIs	https://doi.org/10.1093/tropej/fmr032
Publication status	Published - 1 Feb 2012

Keywords

Blood culture
Children
Nucleic acid amplification test
Rapid diagnostic test
Typhoid fever

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/tropej/fmr032

Cite this

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title = "Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia",

abstract = "Typhoid fever was confirmed by positive blood culture in 5 (3.7\%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 \%) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.",

keywords = "Blood culture, Children, Nucleic acid amplification test, Rapid diagnostic test, Typhoid fever",

author = "Wijedoru, \{Lalith P.M.\} and Varun Kumar and Ngoun Chanpheaktra and Kheng Chheng and Smits, \{Henk L.\} and Rob Pastoor and Nga, \{Tran Vu Thieu\} and Stephen Baker and Vanaporn Wuthiekanun and Peacock, \{Sharon J.\} and Hor Putchhat and Christopher Parry",

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doi = "10.1093/tropej/fmr032",

language = "English",

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journal = "Journal of Tropical Pediatrics",

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TY - JOUR

T1 - Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

AU - Wijedoru, Lalith P.M.

AU - Kumar, Varun

AU - Chanpheaktra, Ngoun

AU - Chheng, Kheng

AU - Smits, Henk L.

AU - Pastoor, Rob

AU - Nga, Tran Vu Thieu

AU - Baker, Stephen

AU - Wuthiekanun, Vanaporn

AU - Peacock, Sharon J.

AU - Putchhat, Hor

AU - Parry, Christopher

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

AB - Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

KW - Blood culture

KW - Children

KW - Nucleic acid amplification test

KW - Rapid diagnostic test

KW - Typhoid fever

U2 - 10.1093/tropej/fmr032

DO - 10.1093/tropej/fmr032

M3 - Article

SN - 0142-6338

VL - 58

SP - 68

EP - 70

JO - Journal of Tropical Pediatrics

JF - Journal of Tropical Pediatrics

IS - 1

M1 - fmr032

ER -

Typhoid Fever among Hospitalized Febrile Children in Siem Reap, Cambodia

Abstract

Keywords

UN SDGs

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