Two Randomized Trials of Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization

Jamie Rylance; Wouter A.A. de Steenhuijsen Piters; Michael J. Mina; Debby Bogaert; Neil French; Daniela Ferreira

doi:10.1164/rccm.201811-2081le

Two Randomized Trials of Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization

Jamie Rylance
, Wouter A.A. de Steenhuijsen Piters
, Michael J. Mina
, Debby Bogaert
, Neil French
, Daniela Ferreira

Research output: Contribution to journal › Letter › peer-review

26 Citations (Scopus)

Abstract

The human nasopharynx is frequently colonized by Streptococcus pneumoniae (the pneumococcus), serving as the reservoir for transmission, a state which necessarily precedes invasive pneumococcal infection. Influenza infection increases pneumococcal colonization density and dysregulates host immune responses, increasing the risk of secondary bacterial pneumonia and death.

Original language	English
Pages (from-to)	1160-1163
Number of pages	4
Journal	American Journal of Respiratory and Critical Care Medicine
Volume	199
Issue number	9
Early online date	13 Feb 2019
DOIs	https://doi.org/10.1164/rccm.201811-2081le
Publication status	Published - 1 May 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Cite this

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title = "Two Randomized Trials of Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization",

abstract = "The human nasopharynx is frequently colonized by Streptococcus pneumoniae (the pneumococcus), serving as the reservoir for transmission, a state which necessarily precedes invasive pneumococcal infection. Influenza infection increases pneumococcal colonization density and dysregulates host immune responses, increasing the risk of secondary bacterial pneumonia and death.",

author = "Jamie Rylance and \{de Steenhuijsen Piters\}, \{Wouter A.A.\} and Mina, \{Michael J.\} and Debby Bogaert and Neil French and Daniela Ferreira",

year = "2019",

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doi = "10.1164/rccm.201811-2081le",

language = "English",

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T1 - Two Randomized Trials of Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization

AU - Rylance, Jamie

AU - de Steenhuijsen Piters, Wouter A.A.

AU - Mina, Michael J.

AU - Bogaert, Debby

AU - French, Neil

AU - Ferreira, Daniela

PY - 2019/5/1

Y1 - 2019/5/1

N2 - The human nasopharynx is frequently colonized by Streptococcus pneumoniae (the pneumococcus), serving as the reservoir for transmission, a state which necessarily precedes invasive pneumococcal infection. Influenza infection increases pneumococcal colonization density and dysregulates host immune responses, increasing the risk of secondary bacterial pneumonia and death.

AB - The human nasopharynx is frequently colonized by Streptococcus pneumoniae (the pneumococcus), serving as the reservoir for transmission, a state which necessarily precedes invasive pneumococcal infection. Influenza infection increases pneumococcal colonization density and dysregulates host immune responses, increasing the risk of secondary bacterial pneumonia and death.

U2 - 10.1164/rccm.201811-2081le

DO - 10.1164/rccm.201811-2081le

M3 - Letter

SN - 1073-449X

VL - 199

SP - 1160

EP - 1163

JO - American Journal of Respiratory and Critical Care Medicine

JF - American Journal of Respiratory and Critical Care Medicine

IS - 9

ER -

Two Randomized Trials of Effect of Live Attenuated Influenza Vaccine on Pneumococcal Colonization

Abstract

UN SDGs

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