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TMPRSS2-mediated SARS-CoV-2 uptake boosts innate immune activation, enhances cytopathology, and drives convergent virus evolution.

  • Bingqian Qu
  • , Csaba Miskey
  • , André Gömer
  • , Robin D.V. Kleinert
  • , Sara Calvo Ibanez
  • , Regina Eberle
  • , Aileen Ebenig
  • , Dylan Postmus
  • , Maximilian K. Nocke
  • , Maike Herrmann
  • , Tabitha K. Itotia
  • , Simon T. Herrmann
  • , Natalie Heinen
  • , Sebastian Höck
  • , Florian D. Hastert
  • , Christine von Rhein
  • , Christoph Schürmann
  • , Xue Li
  • , Ger van Zandbergen
  • , Marek Widera
    • Sandra Ciesek, Barbara S. Schnierle, Alexander W. Tarr, Eike Steinmann, Christine Goffinet, Stephanie Pfaender, Jacomina Krijnse Locker, Michael D. Mühlebach, Daniel Todt, Richard J.P. Brown
  • Paul-Ehrlich-Institut
  • European Virus Bioinformatics Center
  • Ruhr University Bochum
  • Charité – Universitätsmedizin Berlin
  • Chuka University
  • Heidelberg University 
  • Johannes Gutenberg University Mainz
  • Goethe University Frankfurt
  • Fraunhofer Institute for Translational Medicine and Pharmacology ITMP
  • Helmholtz Centre for Infection Research
  • University of Nottingham
  • Leibniz Institute of Virology
  • University of Lübeck
  • Justus Liebig University Giessen
  • German Center for Infection Research partner site Giessen

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

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Immunology and Microbiology