Timing of Screening Benefit for Lung Cancer With Low-Dose CT Imaging

Tao Chen; Yang Xie; Yiyin Zhang; Peng Zhang

doi:10.1016/j.chest.2025.06.012

Timing of Screening Benefit for Lung Cancer With Low-Dose CT Imaging

Tao Chen, Yang Xie, Yiyin Zhang, Peng Zhang

Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Background
Increasing evidence supports lung cancer screening with low-dose CT (LDCT) imaging. However, the benefits of LDCT screening for lung cancer may not be immediate, making it unlikely to benefit patients with limited life expectancy.
Research Question
What is the time to benefit (TTB) from LDCT screening for individuals at high risk for lung cancer?

Original language	English
Pages (from-to)	1049-1056
Number of pages	8
Journal	Chest
Volume	168
Issue number	4
Early online date	18 Jun 2025
DOIs	https://doi.org/10.1016/j.chest.2025.06.012
Publication status	E-pub ahead of print - 18 Jun 2025

Keywords

clinical benefit
low-dose CT
lung cancer
screening

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.chest.2025.06.012

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Licence: CC BY-NC-ND
Embargo ends: 18/06/26

Cite this

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title = "Timing of Screening Benefit for Lung Cancer With Low-Dose CT Imaging",

abstract = "Background Increasing evidence supports lung cancer screening with low-dose CT (LDCT) imaging. However, the benefits of LDCT screening for lung cancer may not be immediate, making it unlikely to benefit patients with limited life expectancy. Research Question What is the time to benefit (TTB) from LDCT screening for individuals at high risk for lung cancer?",

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AU - Chen, Tao

AU - Xie, Yang

AU - Zhang, Yiyin

AU - Zhang, Peng

PY - 2025/6/18

Y1 - 2025/6/18

N2 - Background Increasing evidence supports lung cancer screening with low-dose CT (LDCT) imaging. However, the benefits of LDCT screening for lung cancer may not be immediate, making it unlikely to benefit patients with limited life expectancy. Research Question What is the time to benefit (TTB) from LDCT screening for individuals at high risk for lung cancer?

AB - Background Increasing evidence supports lung cancer screening with low-dose CT (LDCT) imaging. However, the benefits of LDCT screening for lung cancer may not be immediate, making it unlikely to benefit patients with limited life expectancy. Research Question What is the time to benefit (TTB) from LDCT screening for individuals at high risk for lung cancer?

KW - clinical benefit

KW - low-dose CT

KW - lung cancer

KW - screening

U2 - 10.1016/j.chest.2025.06.012

DO - 10.1016/j.chest.2025.06.012

M3 - Article

SN - 0012-3692

VL - 168

SP - 1049

EP - 1056

JO - Chest

JF - Chest

IS - 4

ER -

Timing of Screening Benefit for Lung Cancer With Low-Dose CT Imaging

Abstract

Keywords

UN SDGs

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