The Splenectomy Paradox in Thalassemia: Reduced Transfusion Requirements vs. Accelerated Hepatic Fibrogenesis

Padmapani Padeniya; Dileepa Ediriweera; Madunil Niriella; Arjuna de Silva; Dulani Kottahachchi; Anuja Premawardhena

doi:10.4084/MJHID.2026.023

The Splenectomy Paradox in Thalassemia: Reduced Transfusion Requirements vs. Accelerated Hepatic Fibrogenesis

Padmapani Padeniya
, Dileepa Ediriweera
, Madunil Niriella
, Arjuna de Silva
, Dulani Kottahachchi
, Anuja Premawardhena

Tropical Disease Biology

University of Kelaniya
Adolescent and Adult Thalassaemia Care Center (University Medical Unit)

Research output: Contribution to journal › Letter › peer-review

Original language	English
Article number	e2026023
Journal	Mediterranean Journal of Hematology and Infectious Diseases
Volume	18
Issue number	1
DOIs	https://doi.org/10.4084/MJHID.2026.023
Publication status	Published - 1 Mar 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Liver fibrosis
Liver stiffness measurement
Splenectomy
Transfusion dependent thalassemia

Access to Document

10.4084/MJHID.2026.023Licence: CC BY-NC

Padeniya+PDFFinal published version, 299 KBLicence: CC BY-NC

Cite this

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title = "The Splenectomy Paradox in Thalassemia: Reduced Transfusion Requirements vs. Accelerated Hepatic Fibrogenesis",

keywords = "Liver fibrosis, Liver stiffness measurement, Splenectomy, Transfusion dependent thalassemia",

author = "Padmapani Padeniya and Dileepa Ediriweera and Madunil Niriella and \{de Silva\}, Arjuna and Dulani Kottahachchi and Anuja Premawardhena",

year = "2026",

month = mar,

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doi = "10.4084/MJHID.2026.023",

language = "English",

volume = "18",

journal = "Mediterranean Journal of Hematology and Infectious Diseases",

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TY - JOUR

T1 - The Splenectomy Paradox in Thalassemia: Reduced Transfusion Requirements vs. Accelerated Hepatic Fibrogenesis

AU - Padeniya, Padmapani

AU - Ediriweera, Dileepa

AU - Niriella, Madunil

AU - de Silva, Arjuna

AU - Kottahachchi, Dulani

AU - Premawardhena, Anuja

PY - 2026/3/1

Y1 - 2026/3/1

KW - Liver fibrosis

KW - Liver stiffness measurement

KW - Splenectomy

KW - Transfusion dependent thalassemia

U2 - 10.4084/MJHID.2026.023

DO - 10.4084/MJHID.2026.023

M3 - Letter

AN - SCOPUS:105033486255

SN - 2035-3006

VL - 18

JO - Mediterranean Journal of Hematology and Infectious Diseases

JF - Mediterranean Journal of Hematology and Infectious Diseases

IS - 1

M1 - e2026023

ER -