The molecular basis of insecticide resistance in mosquitoes

Janet Hemingway; Nicola J. Hawkes; Lynn McCarroll; Hilary Ranson

doi:10.1016/j.ibmb.2004.03.018

The molecular basis of insecticide resistance in mosquitoes

Janet Hemingway, Nicola J. Hawkes, Lynn McCarroll, Hilary Ranson

Vector Biology

Liverpool School of Tropical Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

904 Citations (Scopus)

Abstract

Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes. (C) 2004 Elsevier Ltd. All rights reserved.

Original language	English
Title of host publication	Insect Biochemistry and Molecular Biology
Publisher	Elsevier
Pages	653-665
Number of pages	13
Volume	34
Edition	7
DOIs	https://doi.org/10.1016/j.ibmb.2004.03.018
Publication status	Published - 1 Jul 2004

Keywords

Acetylcholinesterase
Carboxylesterase
Esterase
GABA
Glutathione S-transferase (GST)
Insecticide resistance
kdr
Molecular mechanism
P450 monooxygenase
rdl
Sodium channel

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10.1016/j.ibmb.2004.03.018

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title = "The molecular basis of insecticide resistance in mosquitoes",

abstract = "Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes. (C) 2004 Elsevier Ltd. All rights reserved.",

keywords = "Acetylcholinesterase, Carboxylesterase, Esterase, GABA, Glutathione S-transferase (GST), Insecticide resistance, kdr, Molecular mechanism, P450 monooxygenase, rdl, Sodium channel",

author = "Janet Hemingway and Hawkes, \{Nicola J.\} and Lynn McCarroll and Hilary Ranson",

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language = "English",

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booktitle = "Insect Biochemistry and Molecular Biology",

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TY - GEN

T1 - The molecular basis of insecticide resistance in mosquitoes

AU - Hemingway, Janet

AU - Hawkes, Nicola J.

AU - McCarroll, Lynn

AU - Ranson, Hilary

PY - 2004/7/1

Y1 - 2004/7/1

N2 - Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes. (C) 2004 Elsevier Ltd. All rights reserved.

AB - Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes. (C) 2004 Elsevier Ltd. All rights reserved.

KW - Acetylcholinesterase

KW - Carboxylesterase

KW - Esterase

KW - GABA

KW - Glutathione S-transferase (GST)

KW - Insecticide resistance

KW - kdr

KW - Molecular mechanism

KW - P450 monooxygenase

KW - rdl

KW - Sodium channel

U2 - 10.1016/j.ibmb.2004.03.018

DO - 10.1016/j.ibmb.2004.03.018

M3 - Conference contribution

VL - 34

SP - 653

EP - 665

BT - Insect Biochemistry and Molecular Biology

PB - Elsevier

ER -

The molecular basis of insecticide resistance in mosquitoes

Abstract

Keywords

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