The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi

Donnie Mategula; Maureen Ndalama; Clement Lefu; Jobiba Chinkhumba; Latif Ndeketa; Vitumbiko Munthali; Clifford Chitala; Thandizo Malemia; Gertrude Million; Ishmail Mbutuka; Ranken Mhone; Ethel Makwenda; Mussa James; Cornelius Bwanali; Gift Kazembe; Abell Manundo; Evance Chauluka; Salama Chitalo; Ethel Alumando; Dalitso Longwe; Maggie Matandika; Paul Jonasi; Agra Thindwa; Deborah Phiri; Richard Wachepa; Flywell Kawonga; Victor Maiden; Mary Charles; Ida Kapindula; Desiree Witte; Ann M. Turner; Christina Bronowski; Kate Baker; Naor Bar-Zeev; Melita A. Gordon; Queen Dube; Nigel A. Cunliffe; Khuzwayo C. Jere; Jennifer Cornick

doi:10.1093/ofid/ofae050

The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi

Donnie Mategula
, Maureen Ndalama
, Clement Lefu
, Jobiba Chinkhumba
, Latif Ndeketa
, Vitumbiko Munthali
, Clifford Chitala
, Thandizo Malemia
, Gertrude Million
, Ishmail Mbutuka
, Ranken Mhone
, Ethel Makwenda
, Mussa James
, Cornelius Bwanali
, Gift Kazembe
, Abell Manundo
, Evance Chauluka
, Salama Chitalo
, Ethel Alumando
, Dalitso Longwe

Maggie Matandika, Paul Jonasi, Agra Thindwa, Deborah Phiri, Richard Wachepa, Flywell Kawonga, Victor Maiden, Mary Charles, Ida Kapindula, Desiree Witte, Ann M. Turner, Christina Bronowski, Kate Baker, Naor Bar-Zeev, Melita A. Gordon, Queen Dube, Nigel A. Cunliffe, Khuzwayo C. Jere, Jennifer Cornick

Malawi-Liverpool-Wellcome Trust Clinical Research Programme
Kamuzu University of Health Sciences
University of Liverpool
University of Cambridge
World Health Organization
Ministry of Health, Malawi

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Background: Malawi is among 7 countries participating in the Enterics for Global Health (EFGH) Shigella surveillance study, which aims to determine the incidence of medically attended diarrhea attributed to Shigella, a leading bacterial cause of diarrhea in children in low-resource settings.

Methods: We describe the EFGH study site in the densely populated informal settlement of Ndirande Township, Blantyre, Malawi. We explore the site’s geographical location, demographic characteristics, and the healthcare-seeking behavior of its population, particularly for childhood diarrhea. We also describe the management of childhood diarrhea at the health facility, and the associated challenges to attaining optimum adherence to local and national guidelines at the site.

Conclusions: Our overarching aim is to improve global health through understanding and mitigating the impact of diarrhea attributed to Shigella.

Original language	English
Pages (from-to)	S101-S106
Journal	Open Forum Infectious Diseases
Volume	11
Issue number	Supplement_1
Early online date	25 Mar 2024
DOIs	https://doi.org/10.1093/ofid/ofae050
Publication status	Published - 25 Mar 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

diarrhea
health care-seeking behavior
Malawi
Shigella
surveillance

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Ofae050Final published version, 652 KBLicence: CC BY

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Mategula, D., Ndalama, M., Lefu, C., Chinkhumba, J., Ndeketa, L., Munthali, V., Chitala, C., Malemia, T., Million, G., Mbutuka, I., Mhone, R., Makwenda, E., James, M., Bwanali, C., Kazembe, G., Manundo, A., Chauluka, E., Chitalo, S., Alumando, E., ... Cornick, J. (2024). The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi. Open Forum Infectious Diseases, 11(Supplement_1), S101-S106. https://doi.org/10.1093/ofid/ofae050

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title = "The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi",

abstract = "Background: Malawi is among 7 countries participating in the Enterics for Global Health (EFGH) Shigella surveillance study, which aims to determine the incidence of medically attended diarrhea attributed to Shigella, a leading bacterial cause of diarrhea in children in low-resource settings. Methods: We describe the EFGH study site in the densely populated informal settlement of Ndirande Township, Blantyre, Malawi. We explore the site{\textquoteright}s geographical location, demographic characteristics, and the healthcare-seeking behavior of its population, particularly for childhood diarrhea. We also describe the management of childhood diarrhea at the health facility, and the associated challenges to attaining optimum adherence to local and national guidelines at the site. Conclusions: Our overarching aim is to improve global health through understanding and mitigating the impact of diarrhea attributed to Shigella.",

keywords = "diarrhea, health care-seeking behavior, Malawi, Shigella, surveillance",

author = "Donnie Mategula and Maureen Ndalama and Clement Lefu and Jobiba Chinkhumba and Latif Ndeketa and Vitumbiko Munthali and Clifford Chitala and Thandizo Malemia and Gertrude Million and Ishmail Mbutuka and Ranken Mhone and Ethel Makwenda and Mussa James and Cornelius Bwanali and Gift Kazembe and Abell Manundo and Evance Chauluka and Salama Chitalo and Ethel Alumando and Dalitso Longwe and Maggie Matandika and Paul Jonasi and Agra Thindwa and Deborah Phiri and Richard Wachepa and Flywell Kawonga and Victor Maiden and Mary Charles and Ida Kapindula and Desiree Witte and Turner, \{Ann M.\} and Christina Bronowski and Kate Baker and Naor Bar-Zeev and Gordon, \{Melita A.\} and Queen Dube and Cunliffe, \{Nigel A.\} and Jere, \{Khuzwayo C.\} and Jennifer Cornick",

year = "2024",

month = mar,

day = "25",

doi = "10.1093/ofid/ofae050",

language = "English",

volume = "11",

pages = "S101--S106",

journal = "Open Forum Infectious Diseases",

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Mategula, D, Ndalama, M, Lefu, C, Chinkhumba, J, Ndeketa, L, Munthali, V, Chitala, C, Malemia, T, Million, G, Mbutuka, I, Mhone, R, Makwenda, E, James, M, Bwanali, C, Kazembe, G, Manundo, A, Chauluka, E, Chitalo, S, Alumando, E, Longwe, D, Matandika, M, Jonasi, P, Thindwa, A, Phiri, D, Wachepa, R, Kawonga, F, Maiden, V, Charles, M, Kapindula, I, Witte, D, Turner, AM, Bronowski, C, Baker, K, Bar-Zeev, N, Gordon, MA, Dube, Q, Cunliffe, NA, Jere, KC & Cornick, J 2024, 'The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi', Open Forum Infectious Diseases, vol. 11, no. Supplement_1, pp. S101-S106. https://doi.org/10.1093/ofid/ofae050

TY - JOUR

T1 - The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi

AU - Mategula, Donnie

AU - Ndalama, Maureen

AU - Lefu, Clement

AU - Chinkhumba, Jobiba

AU - Ndeketa, Latif

AU - Munthali, Vitumbiko

AU - Chitala, Clifford

AU - Malemia, Thandizo

AU - Million, Gertrude

AU - Mbutuka, Ishmail

AU - Mhone, Ranken

AU - Makwenda, Ethel

AU - James, Mussa

AU - Bwanali, Cornelius

AU - Kazembe, Gift

AU - Manundo, Abell

AU - Chauluka, Evance

AU - Chitalo, Salama

AU - Alumando, Ethel

AU - Longwe, Dalitso

AU - Matandika, Maggie

AU - Jonasi, Paul

AU - Thindwa, Agra

AU - Phiri, Deborah

AU - Wachepa, Richard

AU - Kawonga, Flywell

AU - Maiden, Victor

AU - Charles, Mary

AU - Kapindula, Ida

AU - Witte, Desiree

AU - Turner, Ann M.

AU - Bronowski, Christina

AU - Baker, Kate

AU - Bar-Zeev, Naor

AU - Gordon, Melita A.

AU - Dube, Queen

AU - Cunliffe, Nigel A.

AU - Jere, Khuzwayo C.

AU - Cornick, Jennifer

PY - 2024/3/25

Y1 - 2024/3/25

N2 - Background: Malawi is among 7 countries participating in the Enterics for Global Health (EFGH) Shigella surveillance study, which aims to determine the incidence of medically attended diarrhea attributed to Shigella, a leading bacterial cause of diarrhea in children in low-resource settings. Methods: We describe the EFGH study site in the densely populated informal settlement of Ndirande Township, Blantyre, Malawi. We explore the site’s geographical location, demographic characteristics, and the healthcare-seeking behavior of its population, particularly for childhood diarrhea. We also describe the management of childhood diarrhea at the health facility, and the associated challenges to attaining optimum adherence to local and national guidelines at the site. Conclusions: Our overarching aim is to improve global health through understanding and mitigating the impact of diarrhea attributed to Shigella.

AB - Background: Malawi is among 7 countries participating in the Enterics for Global Health (EFGH) Shigella surveillance study, which aims to determine the incidence of medically attended diarrhea attributed to Shigella, a leading bacterial cause of diarrhea in children in low-resource settings. Methods: We describe the EFGH study site in the densely populated informal settlement of Ndirande Township, Blantyre, Malawi. We explore the site’s geographical location, demographic characteristics, and the healthcare-seeking behavior of its population, particularly for childhood diarrhea. We also describe the management of childhood diarrhea at the health facility, and the associated challenges to attaining optimum adherence to local and national guidelines at the site. Conclusions: Our overarching aim is to improve global health through understanding and mitigating the impact of diarrhea attributed to Shigella.

KW - diarrhea

KW - health care-seeking behavior

KW - Malawi

KW - Shigella

KW - surveillance

U2 - 10.1093/ofid/ofae050

DO - 10.1093/ofid/ofae050

M3 - Article

SN - 2328-8957

VL - 11

SP - S101-S106

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

IS - Supplement_1

ER -

The Enterics for Global Health (EFGH) Shigella Surveillance Study in Malawi

Abstract

UN SDGs

Keywords

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