TY - JOUR
T1 - The efficacy of permethrin-treated bed nets on child mortality and morbidity in western Kenya II. Study design and methods
AU - Phillips-Howard, Penelope
AU - Ter Kuile, Feiko
AU - Nahlen, Bernard L.
AU - Alaii, Jane A.
AU - Gimnig, John E.
AU - Kolczak, Margarette S.
AU - Terlouw, Anja
AU - Kariuki, Simon
AU - Shi, Ya Ping
AU - Kachur, S. Patrick
AU - Hightower, Allen W.
AU - Vulule, John M.
AU - Hawley, William A.
PY - 2003/4/1
Y1 - 2003/4/1
N2 - This paper describes the study design and methods used in a large community-based, group-randomized, controlled trial of permethrin-treated bed nets (ITNs) in an area with intense, perennial malaria transmission in western Kenya conducted between 1996 and 1999. A multi-disciplinary framework was used to explore the efficacy of ITNs in the reduction of all-cause mortality in children less than five years old, the clinical, entomologic, immunologic, and economic impact of ITNs, the social and behavioral determinants of ITN use, and the use of a geographic information system to allow for spatial analyses of these outcomes. Methodologic difficulties encountered in such large-scale field trials are discussed.
AB - This paper describes the study design and methods used in a large community-based, group-randomized, controlled trial of permethrin-treated bed nets (ITNs) in an area with intense, perennial malaria transmission in western Kenya conducted between 1996 and 1999. A multi-disciplinary framework was used to explore the efficacy of ITNs in the reduction of all-cause mortality in children less than five years old, the clinical, entomologic, immunologic, and economic impact of ITNs, the social and behavioral determinants of ITN use, and the use of a geographic information system to allow for spatial analyses of these outcomes. Methodologic difficulties encountered in such large-scale field trials are discussed.
U2 - 10.4269/ajtmh.2003.68.10
DO - 10.4269/ajtmh.2003.68.10
M3 - Article
VL - 68
SP - 10
EP - 15
JO - The American Journal of Tropical Medicine and Hygiene
JF - The American Journal of Tropical Medicine and Hygiene
IS - 4 SUPPL.
ER -
