Splenic lymphoma with villous lymphocytes in tropical West Africa

Imelda Bates; T. Rutherford; D. H. Bevan; G. Bedu-Addo

doi:10.1016/0140-6736(92)92108-r

Splenic lymphoma with villous lymphocytes in tropical West Africa

Imelda Bates, T. Rutherford, D. H. Bevan, G. Bedu-Addo

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Abstract

Splenic lymphoma with villous lymphocytes (SLVL) is a monoclonal B-lymphoproliferative disorder characterised by splenomegaly and distinctive villous lymphocytes in the peripheral blood. It has not previously been reported from Africa, but we describe ten Ghanaian patients with SLVL seen at one hospital during a 4-year period. The clinical presentation is similar in Africa and in temperate regions, though the lymphocyte count is higher in African patients and the disorder predominantly affects middle-aged women rather than elderly men. It is likely that SLVL has previously been classified as splenic chronic lymphocytic leukaemia or hyper-reactive malarial splenomegaly.

Original language	English
Pages (from-to)	575-577
Number of pages	3
Journal	The Lancet
Volume	340
Issue number	8819
DOIs	https://doi.org/10.1016/0140-6736(92)92108-r
Publication status	Published - 5 Sept 1992
Externally published	Yes

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title = "Splenic lymphoma with villous lymphocytes in tropical West Africa",

abstract = "Splenic lymphoma with villous lymphocytes (SLVL) is a monoclonal B-lymphoproliferative disorder characterised by splenomegaly and distinctive villous lymphocytes in the peripheral blood. It has not previously been reported from Africa, but we describe ten Ghanaian patients with SLVL seen at one hospital during a 4-year period. The clinical presentation is similar in Africa and in temperate regions, though the lymphocyte count is higher in African patients and the disorder predominantly affects middle-aged women rather than elderly men. It is likely that SLVL has previously been classified as splenic chronic lymphocytic leukaemia or hyper-reactive malarial splenomegaly.",

author = "Imelda Bates and T. Rutherford and Bevan, \{D. H.\} and G. Bedu-Addo",

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doi = "10.1016/0140-6736(92)92108-r",

language = "English",

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TY - JOUR

T1 - Splenic lymphoma with villous lymphocytes in tropical West Africa

AU - Bates, Imelda

AU - Rutherford, T.

AU - Bevan, D. H.

AU - Bedu-Addo, G.

PY - 1992/9/5

Y1 - 1992/9/5

N2 - Splenic lymphoma with villous lymphocytes (SLVL) is a monoclonal B-lymphoproliferative disorder characterised by splenomegaly and distinctive villous lymphocytes in the peripheral blood. It has not previously been reported from Africa, but we describe ten Ghanaian patients with SLVL seen at one hospital during a 4-year period. The clinical presentation is similar in Africa and in temperate regions, though the lymphocyte count is higher in African patients and the disorder predominantly affects middle-aged women rather than elderly men. It is likely that SLVL has previously been classified as splenic chronic lymphocytic leukaemia or hyper-reactive malarial splenomegaly.

AB - Splenic lymphoma with villous lymphocytes (SLVL) is a monoclonal B-lymphoproliferative disorder characterised by splenomegaly and distinctive villous lymphocytes in the peripheral blood. It has not previously been reported from Africa, but we describe ten Ghanaian patients with SLVL seen at one hospital during a 4-year period. The clinical presentation is similar in Africa and in temperate regions, though the lymphocyte count is higher in African patients and the disorder predominantly affects middle-aged women rather than elderly men. It is likely that SLVL has previously been classified as splenic chronic lymphocytic leukaemia or hyper-reactive malarial splenomegaly.

U2 - 10.1016/0140-6736(92)92108-r

DO - 10.1016/0140-6736(92)92108-r

M3 - Article

SN - 0140-6736

VL - 340

SP - 575

EP - 577

JO - The Lancet

JF - The Lancet

IS - 8819

ER -

Splenic lymphoma with villous lymphocytes in tropical West Africa

Abstract

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