Seroepidemiology and risk factors of hepatitis B virus in Aden, Yemen

Amen Ahmed Bawazir; Christopher Parry; C. Anthony Hart; Tallal A. Sallam; Nicholas Beeching; Luis Cuevas

doi:10.1016/j.jiph.2010.11.003

Seroepidemiology and risk factors of hepatitis B virus in Aden, Yemen

Amen Ahmed Bawazir, Christopher Parry, C. Anthony Hart, Tallal A. Sallam, Nicholas Beeching, Luis Cuevas

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Background

There is little published data concerning hepatitis B virus (HBV) infection in Aden and no data concerning risk factors for infection. This study aimed to determine the prevalence of HBV infection and risk factors for infection in Aden, Yemen.

Methods

A prospective cross sectional survey of individuals attending primary health care facilities was stratified by age and population size. Five hundred and thirty five participants were interviewed and serum was screened for the presence of Immunoglobin G HBV core antibodies (antiHBc). AntiHBc positive participants were tested for antibodies to hepatitis B surface antigen (HBsAg). A case–control analysis of risk factors for HBV was undertaken comparing risk factors between antiHBc positive cases and seronegative controls.

Results

The age-standardized seroprevalence for antiHBc was 16.2% (95% confidence interval (CI) 13.1–19.3) and for HBsAg was 1.5% (95% CI 0.5–2.5). The seroprevalence of antiHBc and HBsAg was estimated to range from 5.5% and 0% in infants to 40% and 4.6% in adults, respectively (p < 0.001). Age (AOR = 1.03, 95% CI = 1.01–1.05), household size (>5–9 members, AOR = 2.9, 95% CI = 1.1–7.6) and ownership of a landline telephone (AOR = 2.8, 95% CI = 1.3–5.8) were independent risk factors for HBV infection.

Conclusions

HBV is still a public health problem in this community, with older individuals having much higher prevalence than younger generations. The results of this study would categorise Aden as a low HBV endemic zone. Perinatal transmission does not seem to be a major route of transmission

Original language	English
Pages (from-to)	48-54
Number of pages	7
Journal	Journal of Infection and Public Health
Volume	4
Issue number	1
DOIs	https://doi.org/10.1016/j.jiph.2010.11.003
Publication status	Published - 1 Mar 2011

Keywords

Aden
Hepatitis B virus
Risk factors
Seroepidemiology
Yemen

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jiph.2010.11.003

Cite this

@article{a1819e98968b4c9797058727be5347ee,

title = "Seroepidemiology and risk factors of hepatitis B virus in Aden, Yemen",

abstract = "BackgroundThere is little published data concerning hepatitis B virus (HBV) infection in Aden and no data concerning risk factors for infection. This study aimed to determine the prevalence of HBV infection and risk factors for infection in Aden, Yemen.MethodsA prospective cross sectional survey of individuals attending primary health care facilities was stratified by age and population size. Five hundred and thirty five participants were interviewed and serum was screened for the presence of Immunoglobin G HBV core antibodies (antiHBc). AntiHBc positive participants were tested for antibodies to hepatitis B surface antigen (HBsAg). A case–control analysis of risk factors for HBV was undertaken comparing risk factors between antiHBc positive cases and seronegative controls.ResultsThe age-standardized seroprevalence for antiHBc was 16.2% (95% confidence interval (CI) 13.1–19.3) and for HBsAg was 1.5% (95% CI 0.5–2.5). The seroprevalence of antiHBc and HBsAg was estimated to range from 5.5% and 0% in infants to 40% and 4.6% in adults, respectively (p < 0.001). Age (AOR = 1.03, 95% CI = 1.01–1.05), household size (>5–9 members, AOR = 2.9, 95% CI = 1.1–7.6) and ownership of a landline telephone (AOR = 2.8, 95% CI = 1.3–5.8) were independent risk factors for HBV infection.ConclusionsHBV is still a public health problem in this community, with older individuals having much higher prevalence than younger generations. The results of this study would categorise Aden as a low HBV endemic zone. Perinatal transmission does not seem to be a major route of transmission",

keywords = "Aden, Hepatitis B virus, Risk factors, Seroepidemiology, Yemen",

author = "Bawazir, {Amen Ahmed} and Christopher Parry and Hart, {C. Anthony} and Sallam, {Tallal A.} and Nicholas Beeching and Luis Cuevas",

year = "2011",

month = mar,

day = "1",

doi = "10.1016/j.jiph.2010.11.003",

language = "English",

volume = "4",

pages = "48--54",

journal = "Journal of Infection and Public Health",

issn = "1876-0341",

publisher = "Elsevier Ltd",

number = "1",

}

TY - JOUR

T1 - Seroepidemiology and risk factors of hepatitis B virus in Aden, Yemen

AU - Bawazir, Amen Ahmed

AU - Parry, Christopher

AU - Hart, C. Anthony

AU - Sallam, Tallal A.

AU - Beeching, Nicholas

AU - Cuevas, Luis

PY - 2011/3/1

Y1 - 2011/3/1

N2 - BackgroundThere is little published data concerning hepatitis B virus (HBV) infection in Aden and no data concerning risk factors for infection. This study aimed to determine the prevalence of HBV infection and risk factors for infection in Aden, Yemen.MethodsA prospective cross sectional survey of individuals attending primary health care facilities was stratified by age and population size. Five hundred and thirty five participants were interviewed and serum was screened for the presence of Immunoglobin G HBV core antibodies (antiHBc). AntiHBc positive participants were tested for antibodies to hepatitis B surface antigen (HBsAg). A case–control analysis of risk factors for HBV was undertaken comparing risk factors between antiHBc positive cases and seronegative controls.ResultsThe age-standardized seroprevalence for antiHBc was 16.2% (95% confidence interval (CI) 13.1–19.3) and for HBsAg was 1.5% (95% CI 0.5–2.5). The seroprevalence of antiHBc and HBsAg was estimated to range from 5.5% and 0% in infants to 40% and 4.6% in adults, respectively (p < 0.001). Age (AOR = 1.03, 95% CI = 1.01–1.05), household size (>5–9 members, AOR = 2.9, 95% CI = 1.1–7.6) and ownership of a landline telephone (AOR = 2.8, 95% CI = 1.3–5.8) were independent risk factors for HBV infection.ConclusionsHBV is still a public health problem in this community, with older individuals having much higher prevalence than younger generations. The results of this study would categorise Aden as a low HBV endemic zone. Perinatal transmission does not seem to be a major route of transmission

AB - BackgroundThere is little published data concerning hepatitis B virus (HBV) infection in Aden and no data concerning risk factors for infection. This study aimed to determine the prevalence of HBV infection and risk factors for infection in Aden, Yemen.MethodsA prospective cross sectional survey of individuals attending primary health care facilities was stratified by age and population size. Five hundred and thirty five participants were interviewed and serum was screened for the presence of Immunoglobin G HBV core antibodies (antiHBc). AntiHBc positive participants were tested for antibodies to hepatitis B surface antigen (HBsAg). A case–control analysis of risk factors for HBV was undertaken comparing risk factors between antiHBc positive cases and seronegative controls.ResultsThe age-standardized seroprevalence for antiHBc was 16.2% (95% confidence interval (CI) 13.1–19.3) and for HBsAg was 1.5% (95% CI 0.5–2.5). The seroprevalence of antiHBc and HBsAg was estimated to range from 5.5% and 0% in infants to 40% and 4.6% in adults, respectively (p < 0.001). Age (AOR = 1.03, 95% CI = 1.01–1.05), household size (>5–9 members, AOR = 2.9, 95% CI = 1.1–7.6) and ownership of a landline telephone (AOR = 2.8, 95% CI = 1.3–5.8) were independent risk factors for HBV infection.ConclusionsHBV is still a public health problem in this community, with older individuals having much higher prevalence than younger generations. The results of this study would categorise Aden as a low HBV endemic zone. Perinatal transmission does not seem to be a major route of transmission

KW - Aden

KW - Hepatitis B virus

KW - Risk factors

KW - Seroepidemiology

KW - Yemen

U2 - 10.1016/j.jiph.2010.11.003

DO - 10.1016/j.jiph.2010.11.003

M3 - Article

SN - 1876-0341

VL - 4

SP - 48

EP - 54

JO - Journal of Infection and Public Health

JF - Journal of Infection and Public Health

IS - 1

ER -

Seroepidemiology and risk factors of hepatitis B virus in Aden, Yemen

Abstract

Keywords

UN SDGs

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