Schistosomiasis in African infants and preschool children: let them now be treated!

Russell Stothard; José C. Sousa-Figueiredo; Martha Betson; Amaya Bustinduy; Jutta Reinhard-Rupp

doi:10.1016/j.pt.2013.02.001

Schistosomiasis in African infants and preschool children: let them now be treated!

Russell Stothard, José C. Sousa-Figueiredo, Martha Betson, Amaya Bustinduy, Jutta Reinhard-Rupp

Tropical Disease Biology

Research output: Contribution to journal › Review article › peer-review

155 Citations (Scopus)

Abstract

The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.

Original language	English
Pages (from-to)	197-205
Number of pages	9
Journal	Trends In Parasitology
Volume	29
Issue number	4
DOIs	https://doi.org/10.1016/j.pt.2013.02.001
Publication status	Published - 5 Mar 2013

Keywords

Cure rates
HIV
Malaria
Neglected tropical diseases
Paediatrics
Pharmacokinetics
Praziquantel
Preventive chemotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pt.2013.02.001Licence: CC BY

Cite this

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title = "Schistosomiasis in African infants and preschool children: let them now be treated!",

abstract = "The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.",

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T1 - Schistosomiasis in African infants and preschool children: let them now be treated!

AU - Stothard, Russell

AU - Sousa-Figueiredo, José C.

AU - Betson, Martha

AU - Bustinduy, Amaya

AU - Reinhard-Rupp, Jutta

PY - 2013/3/5

Y1 - 2013/3/5

N2 - The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.

AB - The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.

KW - Cure rates

KW - HIV

KW - Malaria

KW - Neglected tropical diseases

KW - Paediatrics

KW - Pharmacokinetics

KW - Praziquantel

KW - Preventive chemotherapy

U2 - 10.1016/j.pt.2013.02.001

DO - 10.1016/j.pt.2013.02.001

M3 - Review article

SN - 1471-4922

VL - 29

SP - 197

EP - 205

JO - Trends In Parasitology

JF - Trends In Parasitology

IS - 4

ER -

Schistosomiasis in African infants and preschool children: let them now be treated!

Abstract

Keywords

UN SDGs

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