Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance

Steven Riley; Kylie E.C. Ainslie; Oliver Eales; Caroline E. Walters; Haowei Wang; Christina Atchison; Claudio Fronterre; Peter Diggle; Deborah Ashby; Christl A. Donnelly; Graham Cooke; Wendy Barclay; Helen Ward; Ara Darzi; Paul Elliott

doi:10.1126/science.abf0874

Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance

Steven Riley
, Kylie E.C. Ainslie
, Oliver Eales
, Caroline E. Walters
, Haowei Wang
, Christina Atchison
, Claudio Fronterre
, Peter Diggle
, Deborah Ashby
, Christl A. Donnelly
, Graham Cooke
, Wendy Barclay
, Helen Ward
, Ara Darzi
, Paul Elliott

Imperial College London
Lancaster University
Health Data Research UK
University of Oxford
Imperial College Healthcare NHS Trust
NIHR Imperial Clinical Research Facility and NIHR Imperial Biomedical Research Centre

Research output: Contribution to journal › Article › peer-review

66 Citations (Scopus)

Abstract

Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.

Original language	English
Pages (from-to)	990-995
Number of pages	6
Journal	Science
Volume	372
Issue number	6545
DOIs	https://doi.org/10.1126/science.abf0874
Publication status	Published - 28 May 2021
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1126/science.abf0874Licence: CC BY

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Riley, S., Ainslie, K. E. C., Eales, O., Walters, C. E., Wang, H., Atchison, C., Fronterre, C., Diggle, P., Ashby, D., Donnelly, C. A., Cooke, G., Barclay, W., Ward, H., Darzi, A., & Elliott, P. (2021). Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance. Science, 372(6545), 990-995. https://doi.org/10.1126/science.abf0874

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title = "Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance",

abstract = "Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from \textasciitilde{}594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.",

author = "Steven Riley and Ainslie, \{Kylie E.C.\} and Oliver Eales and Walters, \{Caroline E.\} and Haowei Wang and Christina Atchison and Claudio Fronterre and Peter Diggle and Deborah Ashby and Donnelly, \{Christl A.\} and Graham Cooke and Wendy Barclay and Helen Ward and Ara Darzi and Paul Elliott",

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doi = "10.1126/science.abf0874",

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Riley, S, Ainslie, KEC, Eales, O, Walters, CE, Wang, H, Atchison, C, Fronterre, C, Diggle, P, Ashby, D, Donnelly, CA, Cooke, G, Barclay, W, Ward, H, Darzi, A & Elliott, P 2021, 'Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance', Science, vol. 372, no. 6545, pp. 990-995. https://doi.org/10.1126/science.abf0874

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T1 - Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance

AU - Riley, Steven

AU - Ainslie, Kylie E.C.

AU - Eales, Oliver

AU - Walters, Caroline E.

AU - Wang, Haowei

AU - Atchison, Christina

AU - Fronterre, Claudio

AU - Diggle, Peter

AU - Ashby, Deborah

AU - Donnelly, Christl A.

AU - Cooke, Graham

AU - Barclay, Wendy

AU - Ward, Helen

AU - Darzi, Ara

AU - Elliott, Paul

PY - 2021/5/28

Y1 - 2021/5/28

N2 - Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.

AB - Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.

U2 - 10.1126/science.abf0874

DO - 10.1126/science.abf0874

M3 - Article

SN - 0036-8075

VL - 372

SP - 990

EP - 995

JO - Science

JF - Science

IS - 6545

ER -

Resurgence of SARS-CoV-2: Detection by community viral surveillance: Detection by community viral surveillance

Abstract

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