Primary Care Influenza-like Illness Surveillance in Ho Chi Minh City, Vietnam 2013-2015

Stacy Todd; Nguyen Thi Cam Huong; Nguyen Thi Le Thanh; Nguyen Ha Thao Vy; Nguyen Thanh Hung; Tran Thi Nhu Thao; Huynh Thi Phuong; Rogier van Doorn; Vu Thi Ty Hang; Nguyen Van Vinh Chau; Jonathan M. Read; David Lalloo; Maciej F. Boni

doi:10.1111/irv.12574

Primary Care Influenza-like Illness Surveillance in Ho Chi Minh City, Vietnam 2013-2015

Stacy Todd, Nguyen Thi Cam Huong, Nguyen Thi Le Thanh, Nguyen Ha Thao Vy, Nguyen Thanh Hung, Tran Thi Nhu Thao, Huynh Thi Phuong, Rogier van Doorn, Vu Thi Ty Hang, Nguyen Van Vinh Chau, Jonathan M. Read, David Lalloo, Maciej F. Boni

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Background

Year-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics.

Methods

An observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed.

Results

A total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3%) despite limited evidence of bacterial infection.

Conclusion

Influenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.

Original language	English
Pages (from-to)	623-631
Number of pages	9
Journal	Influenza and other Respiratory Viruses
Volume	12
Issue number	5
Early online date	2 Jun 2018
DOIs	https://doi.org/10.1111/irv.12574
Publication status	Published - 1 Sept 2018

Keywords

epidemiology
human
influenza
primary health care
Vietnam

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/irv.12574Licence: CC BY

Todd et al-2018-Influenza and Other Respiratory VirusesAccepted author manuscript, 278 KBLicence: CC BY

Cite this

Todd, S., Huong, N. T. C., Thanh, N. T. L., Vy, N. H. T., Hung, N. T., Thao, T. T. N., Phuong, H. T., van Doorn, R., Hang, V. T. T., Chau, N. V. V., Read, J. M., Lalloo, D., & Boni, M. F. (2018). Primary Care Influenza-like Illness Surveillance in Ho Chi Minh City, Vietnam 2013-2015. Influenza and other Respiratory Viruses, 12(5), 623-631. https://doi.org/10.1111/irv.12574

@article{73ae14df6ffa4e8f8087511662e53db8,

title = "Primary Care Influenza-like Illness Surveillance in Ho Chi Minh City, Vietnam 2013-2015",

abstract = "BackgroundYear-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics.MethodsAn observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed.ResultsA total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81\% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3\%) despite limited evidence of bacterial infection.ConclusionInfluenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.",

keywords = "epidemiology, human, influenza, primary health care, Vietnam",

author = "Stacy Todd and Huong, \{Nguyen Thi Cam\} and Thanh, \{Nguyen Thi Le\} and Vy, \{Nguyen Ha Thao\} and Hung, \{Nguyen Thanh\} and Thao, \{Tran Thi Nhu\} and Phuong, \{Huynh Thi\} and \{van Doorn\}, Rogier and Hang, \{Vu Thi Ty\} and Chau, \{Nguyen Van Vinh\} and Read, \{Jonathan M.\} and David Lalloo and Boni, \{Maciej F.\}",

year = "2018",

month = sep,

day = "1",

doi = "10.1111/irv.12574",

language = "English",

volume = "12",

pages = "623--631",

journal = "Influenza and other Respiratory Viruses",

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publisher = "Wiley-Blackwell Publishing Ltd",

number = "5",

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TY - JOUR

T1 - Primary Care Influenza-like Illness Surveillance in Ho Chi Minh City, Vietnam 2013-2015

AU - Todd, Stacy

AU - Huong, Nguyen Thi Cam

AU - Thanh, Nguyen Thi Le

AU - Vy, Nguyen Ha Thao

AU - Hung, Nguyen Thanh

AU - Thao, Tran Thi Nhu

AU - Phuong, Huynh Thi

AU - van Doorn, Rogier

AU - Hang, Vu Thi Ty

AU - Chau, Nguyen Van Vinh

AU - Read, Jonathan M.

AU - Lalloo, David

AU - Boni, Maciej F.

PY - 2018/9/1

Y1 - 2018/9/1

N2 - BackgroundYear-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics.MethodsAn observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed.ResultsA total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3%) despite limited evidence of bacterial infection.ConclusionInfluenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.

AB - BackgroundYear-round transmission of influenza has been detected in Vietnam through both national surveillance and other epidemiological studies. Understanding the demographic and clinical features of influenza-like illness (ILI) presenting to primary care in urban Vietnam is vital to understand these transmission dynamics.MethodsAn observational study of patients with ILI in Ho Chi Minh City, Vietnam, was conducted between August 2013 and November 2015 in a mix of public and private primary care settings. Molecular testing for influenza A and influenza B and 12 other respiratory viruses was performed.ResultsA total of 1152 ILI patients were recruited. 322 and 136 subjects tested positive for influenza A and influenza B, respectively. 193 subjects tested positive for another respiratory virus; most commonly rhinovirus and parainfluenza virus 3. Influenza was detected in 81% of the 116 study weeks. Three peaks of influenza activity were detected; an H3N2 peak April-June 2014, an influenza B peak July-December 2014, and a mixed H3N2 and H1N1 peak March-September 2015. Subjects recruited from private clinics were more likely to have higher income and to have reported previous influenza vaccination. Antibiotic use was common (50.3%) despite limited evidence of bacterial infection.ConclusionInfluenza in southern Vietnam has complex transmission dynamics including periods of intense influenza activity of alternating types and subtypes. Broadening surveillance from hospital to the community in tropical settings is feasible and a valuable for improving our understanding of the global spread and evolution of the virus.

KW - epidemiology

KW - human

KW - influenza

KW - primary health care

KW - Vietnam

U2 - 10.1111/irv.12574

DO - 10.1111/irv.12574

M3 - Article

SN - 1750-2640

VL - 12

SP - 623

EP - 631

JO - Influenza and other Respiratory Viruses

JF - Influenza and other Respiratory Viruses

IS - 5

ER -

Primary Care Influenza-like Illness Surveillance in Ho Chi Minh City, Vietnam 2013-2015

Abstract

Keywords

UN SDGs

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