Abstract
Prevention is the key to stop transmission of TB. It consists of early diagnosis and treatment of active TB to stop infectiousness, the prevention of active disease in exposed or known latently infected individuals and vaccination. Vaccination with the Bacillus Calmette-Guerin (BCG) vaccine is unfortunately largely ineffective in interrupting transmission. However a more powerful vaccine will have the potential to cause a major shift in the management of TB. In this chapter prophylactic treatment in latently infected and HIV infected patients is reviewed. Additionally the prevention of active disease in MDR-exposed persons and vaccine development will be discussed.
| Original language | English |
|---|---|
| Title of host publication | SpringerBriefs in Public Health |
| Pages | 51-56 |
| Number of pages | 6 |
| DOIs | |
| Publication status | Published - 1 Jan 2015 |
Keywords
- Latent tuberculosis
- Prevention
- Prophylactic treatment
- Prophylactic treatment in multi-drug resistant tuberculosis
- Vaccine