Prevalence and determinants of chronic respiratory diseases in adults in rural Sudan

R. Ahmed; R. Osman; Becky Nightingale; D. Nagem; Rachael Thomson; R. Malmborg; M. Elmustafa; A. F.S. Amaral; J. Patel; P. Burney; A. El Sony; Kevin Mortimer

doi:10.5588/ijtld.22.0655

Prevalence and determinants of chronic respiratory diseases in adults in rural Sudan

R. Ahmed
, R. Osman
, Becky Nightingale
, D. Nagem
, Rachael Thomson
, R. Malmborg
, M. Elmustafa
, A. F.S. Amaral
, J. Patel
, P. Burney
, A. El Sony
, Kevin Mortimer

Epidemiological Laboratory
Nordic Innovation Centre
University of Gezira
Wad Medani College of Medical Sciences and Technology
Imperial College London
Liverpool University Hospitals NHS Foundation Trust
University of Cambridge
University of KwaZulu-Natal

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

BACKGROUND:

Chronic respiratory diseases (CRDs) greatly contribute to worldwide mortality. Despite new data emerging from Africa, prevalence estimates and determinants of CRDs in rural settings are limited. This study sought to extend the existing research conducted in urban Sudan by conducting a rural comparison.

METHODS:

Participants aged ≥18 years (n = 1,850), living in rural Gezira State completed pre-and post-bronchodilator spirometry and a questionnaire. Prevalence of respiratory symptoms and spirometric abnormalities were reported. Regression analyses were used to identify risk factors for CRDs.

RESULTS:

Prevalence of chronic airflow obstruction (CAO) was 4.1% overall and 5.5% in those aged ≥40 years. Reversibility was seen in 6.4%. Low forced vital capacity (FVC) was seen in 58.5%, and at least one respiratory symptom was present in 40.7% of the participants. CAO was more common among people aged 60-69 years (OR 2.07, 95% CI 1.13-3.82) and less common among highly educated participants (OR 0.50, 95% CI 0.27-0.93). Being underweight was associated with lower FVC (OR 3.07, 95% CI 2.24-4.20).

CONCLUSIONS:

A substantial burden of CRD exists among adults in rural Sudan. Investment in CRD prevention and management strategies is needed.

Original language	English
Pages (from-to)	841-849
Number of pages	9
Journal	International Journal of Tuberculosis and Lung Disease
Volume	27
Issue number	11
DOIs	https://doi.org/10.5588/ijtld.22.0655
Publication status	Published - 1 Nov 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

asthma
CAO
COPD
CRD
low FVC

Access to Document

10.5588/ijtld.22.0655Licence: CC BY

PMC10599415Final published version, 291 KBLicence: CC BY

Cite this

@article{276e07bb572046bb92745790b645b1ff,

title = "Prevalence and determinants of chronic respiratory diseases in adults in rural Sudan",

abstract = "BACKGROUND:Chronic respiratory diseases (CRDs) greatly contribute to worldwide mortality. Despite new data emerging from Africa, prevalence estimates and determinants of CRDs in rural settings are limited. This study sought to extend the existing research conducted in urban Sudan by conducting a rural comparison.METHODS:Participants aged ≥18 years (n = 1,850), living in rural Gezira State completed pre-and post-bronchodilator spirometry and a questionnaire. Prevalence of respiratory symptoms and spirometric abnormalities were reported. Regression analyses were used to identify risk factors for CRDs.RESULTS:Prevalence of chronic airflow obstruction (CAO) was 4.1\% overall and 5.5\% in those aged ≥40 years. Reversibility was seen in 6.4\%. Low forced vital capacity (FVC) was seen in 58.5\%, and at least one respiratory symptom was present in 40.7\% of the participants. CAO was more common among people aged 60-69 years (OR 2.07, 95\% CI 1.13-3.82) and less common among highly educated participants (OR 0.50, 95\% CI 0.27-0.93). Being underweight was associated with lower FVC (OR 3.07, 95\% CI 2.24-4.20).CONCLUSIONS:A substantial burden of CRD exists among adults in rural Sudan. Investment in CRD prevention and management strategies is needed.",

keywords = "asthma, CAO, COPD, CRD, low FVC",

author = "R. Ahmed and R. Osman and Becky Nightingale and D. Nagem and Rachael Thomson and R. Malmborg and M. Elmustafa and Amaral, \{A. F.S.\} and J. Patel and P. Burney and \{El Sony\}, A. and Kevin Mortimer",

year = "2023",

month = nov,

day = "1",

doi = "10.5588/ijtld.22.0655",

language = "English",

volume = "27",

pages = "841--849",

journal = "International Journal of Tuberculosis and Lung Disease",

issn = "1027-3719",

publisher = "International Union Against Tuberculosis and Lung Disease ",

number = "11",

}

TY - JOUR

T1 - Prevalence and determinants of chronic respiratory diseases in adults in rural Sudan

AU - Ahmed, R.

AU - Osman, R.

AU - Nightingale, Becky

AU - Nagem, D.

AU - Thomson, Rachael

AU - Malmborg, R.

AU - Elmustafa, M.

AU - Amaral, A. F.S.

AU - Patel, J.

AU - Burney, P.

AU - El Sony, A.

AU - Mortimer, Kevin

PY - 2023/11/1

Y1 - 2023/11/1

N2 - BACKGROUND:Chronic respiratory diseases (CRDs) greatly contribute to worldwide mortality. Despite new data emerging from Africa, prevalence estimates and determinants of CRDs in rural settings are limited. This study sought to extend the existing research conducted in urban Sudan by conducting a rural comparison.METHODS:Participants aged ≥18 years (n = 1,850), living in rural Gezira State completed pre-and post-bronchodilator spirometry and a questionnaire. Prevalence of respiratory symptoms and spirometric abnormalities were reported. Regression analyses were used to identify risk factors for CRDs.RESULTS:Prevalence of chronic airflow obstruction (CAO) was 4.1% overall and 5.5% in those aged ≥40 years. Reversibility was seen in 6.4%. Low forced vital capacity (FVC) was seen in 58.5%, and at least one respiratory symptom was present in 40.7% of the participants. CAO was more common among people aged 60-69 years (OR 2.07, 95% CI 1.13-3.82) and less common among highly educated participants (OR 0.50, 95% CI 0.27-0.93). Being underweight was associated with lower FVC (OR 3.07, 95% CI 2.24-4.20).CONCLUSIONS:A substantial burden of CRD exists among adults in rural Sudan. Investment in CRD prevention and management strategies is needed.

AB - BACKGROUND:Chronic respiratory diseases (CRDs) greatly contribute to worldwide mortality. Despite new data emerging from Africa, prevalence estimates and determinants of CRDs in rural settings are limited. This study sought to extend the existing research conducted in urban Sudan by conducting a rural comparison.METHODS:Participants aged ≥18 years (n = 1,850), living in rural Gezira State completed pre-and post-bronchodilator spirometry and a questionnaire. Prevalence of respiratory symptoms and spirometric abnormalities were reported. Regression analyses were used to identify risk factors for CRDs.RESULTS:Prevalence of chronic airflow obstruction (CAO) was 4.1% overall and 5.5% in those aged ≥40 years. Reversibility was seen in 6.4%. Low forced vital capacity (FVC) was seen in 58.5%, and at least one respiratory symptom was present in 40.7% of the participants. CAO was more common among people aged 60-69 years (OR 2.07, 95% CI 1.13-3.82) and less common among highly educated participants (OR 0.50, 95% CI 0.27-0.93). Being underweight was associated with lower FVC (OR 3.07, 95% CI 2.24-4.20).CONCLUSIONS:A substantial burden of CRD exists among adults in rural Sudan. Investment in CRD prevention and management strategies is needed.

KW - asthma

KW - CAO

KW - COPD

KW - CRD

KW - low FVC

U2 - 10.5588/ijtld.22.0655

DO - 10.5588/ijtld.22.0655

M3 - Article

SN - 1027-3719

VL - 27

SP - 841

EP - 849

JO - International Journal of Tuberculosis and Lung Disease

JF - International Journal of Tuberculosis and Lung Disease

IS - 11

ER -

Prevalence and determinants of chronic respiratory diseases in adults in rural Sudan

Abstract

UN SDGs

Keywords

Access to Document

Fingerprint

Cite this