Pneumococcal conjugate vaccines for preventing acute otitis media in children

Joline LH Sévaux, Roderick P Venekamp, Vittoria Lutje, Eelko Hak, Anne Schilder, Elisabeth Sanders, Roger Damoiseaux

Research output: Contribution to journalReview articlepeer-review

16 Citations (Scopus)

Abstract

Background

Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from the middle ear fluid of children with acute otitis media (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead to a decline in AOM. The effects of PCVs deserve ongoing monitoring since studies from the post‐PCV era report a shift in causative otopathogens towards non‐vaccine serotypes and other bacteria. This updated Cochrane Review was first published in 2002 and updated in 2004, 2009, 2014, and 2019.

Original languageEnglish
Article numberCD001480
Pages (from-to)CD001480
JournalCochrane Database of Systematic Reviews
Volume2020
Issue number11
DOIs
Publication statusPublished - 24 Nov 2020

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