Pilot study on multidrug resistant tuberculosis in Nigeria

L. Lawson; A. G. Habib; M. I. Okobi; D. Idiong; I. Olajide; N. Emenyonu; N. Onuoha; Luis Cuevas; S. O. Ogiri

doi:10.4103/1596-3519.68355

Pilot study on multidrug resistant tuberculosis in Nigeria

L. Lawson, A. G. Habib, M. I. Okobi, D. Idiong, I. Olajide, N. Emenyonu, N. Onuoha, Luis Cuevas, S. O. Ogiri

Clinical Sciences

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.

Original language	English
Pages (from-to)	184-187
Number of pages	4
Journal	Annals of African Medicine
Volume	9
Issue number	3
DOIs	https://doi.org/10.4103/1596-3519.68355
Publication status	Published - 1 Sept 2010

Keywords

Drug resistance
human immunodeficiency virus
Nigeria
prevalence
tuberculosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4103/1596-3519.68355

Cite this

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abstract = "Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31\%) of 32 culture-positive patients were resistant to at least one and four (13\%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.",

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T1 - Pilot study on multidrug resistant tuberculosis in Nigeria

AU - Lawson, L.

AU - Habib, A. G.

AU - Okobi, M. I.

AU - Idiong, D.

AU - Olajide, I.

AU - Emenyonu, N.

AU - Onuoha, N.

AU - Cuevas, Luis

AU - Ogiri, S. O.

PY - 2010/9/1

Y1 - 2010/9/1

N2 - Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.

AB - Background: Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients. Methods: Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria. Results: Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found. Conclusions: MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.

KW - Drug resistance

KW - human immunodeficiency virus

KW - Nigeria

KW - prevalence

KW - tuberculosis

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DO - 10.4103/1596-3519.68355

M3 - Article

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VL - 9

SP - 184

EP - 187

JO - Annals of African Medicine

JF - Annals of African Medicine

IS - 3

ER -

Pilot study on multidrug resistant tuberculosis in Nigeria

Abstract

Keywords

UN SDGs

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