Over-testing Galactomannan in patients with hematological malignancies: A retrospective analysis from a tertiary care university hospital in Türkiye

Ilkay Bozkurt

doi:10.1016/j.diagmicrobio.2026.117284

Over-testing Galactomannan in patients with hematological malignancies: A retrospective analysis from a tertiary care university hospital in Türkiye

Ilkay Bozkurt

Research output: Contribution to journal › Comment/debate

Abstract

This study aimed to evaluate the Galactomannan (GM) correlation with radiologic findings, treatment decisions and financial impact of over-testing. In this cohort, GM testing yielded a low diagnostic return, requiring 53 tests to obtain one positive result and 103 tests to identify a probable invasive aspergillosis (IA) case, generating a considerable avoidable financial burden. These findings highlight the need to rationalize GM utilization and align testing with IA risk to reduce hospital costs.

Original language	English
Article number	117284
Journal	Diagnostic Microbiology and Infectious Disease
Volume	115
Issue number	1
Early online date	31 Jan 2026
DOIs	https://doi.org/10.1016/j.diagmicrobio.2026.117284
Publication status	E-pub ahead of print - 31 Jan 2026
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Galactomannan
Hematology
Malignancy

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10.1016/j.diagmicrobio.2026.117284Licence: Other

Cite this

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title = "Over-testing Galactomannan in patients with hematological malignancies: A retrospective analysis from a tertiary care university hospital in T{\"u}rkiye",

abstract = "This study aimed to evaluate the Galactomannan (GM) correlation with radiologic findings, treatment decisions and financial impact of over-testing. In this cohort, GM testing yielded a low diagnostic return, requiring 53 tests to obtain one positive result and 103 tests to identify a probable invasive aspergillosis (IA) case, generating a considerable avoidable financial burden. These findings highlight the need to rationalize GM utilization and align testing with IA risk to reduce hospital costs.",

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N2 - This study aimed to evaluate the Galactomannan (GM) correlation with radiologic findings, treatment decisions and financial impact of over-testing. In this cohort, GM testing yielded a low diagnostic return, requiring 53 tests to obtain one positive result and 103 tests to identify a probable invasive aspergillosis (IA) case, generating a considerable avoidable financial burden. These findings highlight the need to rationalize GM utilization and align testing with IA risk to reduce hospital costs.

AB - This study aimed to evaluate the Galactomannan (GM) correlation with radiologic findings, treatment decisions and financial impact of over-testing. In this cohort, GM testing yielded a low diagnostic return, requiring 53 tests to obtain one positive result and 103 tests to identify a probable invasive aspergillosis (IA) case, generating a considerable avoidable financial burden. These findings highlight the need to rationalize GM utilization and align testing with IA risk to reduce hospital costs.

KW - Galactomannan

KW - Hematology

KW - Malignancy

U2 - 10.1016/j.diagmicrobio.2026.117284

DO - 10.1016/j.diagmicrobio.2026.117284

M3 - Comment/debate

AN - SCOPUS:105028761131

SN - 0732-8893

VL - 115

JO - Diagnostic Microbiology and Infectious Disease

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ER -

Over-testing Galactomannan in patients with hematological malignancies: A retrospective analysis from a tertiary care university hospital in Türkiye

Abstract

UN SDGs

Keywords

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