Need for a paradigm shift in soil-transmitted helminthiasis control: Targeting the right people, in the right place, and with the right drug(s)

Paul M. Emerson; Darin Evans; Matthew C. Freeman; Christy Hanson; Khumbo Kalua; Jennifer Keiser; Alejandro Krolewiecki; Lynn Leonard; Bruno Levecke; Sultani Matendechero; Arianna Rubin Means; Antonio Montresor; Denise Mupfasoni; Rachel L. Pullan; Lisa A. Rotondo; Mariana Stephens; Kristin M. Sullivan; Judd L. Walson; Tijana Williams; Jürg Utzinger

doi:10.1371/journal.pntd.0012521

Need for a paradigm shift in soil-transmitted helminthiasis control: Targeting the right people, in the right place, and with the right drug(s)

Paul M. Emerson
, Darin Evans
, Matthew C. Freeman
, Christy Hanson
, Khumbo Kalua
, Jennifer Keiser
, Alejandro Krolewiecki
, Lynn Leonard
, Bruno Levecke
, Sultani Matendechero
, Arianna Rubin Means
, Antonio Montresor
, Denise Mupfasoni
, Rachel L. Pullan
, Lisa A. Rotondo
, Mariana Stephens
, Kristin M. Sullivan
, Judd L. Walson
, Tijana Williams
, Jürg Utzinger

Task Force for Global Health
United States Agency for International Development
Emory University
Gates Foundation
Blantyre Institute for Community Outreach
Swiss TPH
University of Basel
Universidad Nacional de Salta
Fundacion Mundo Sano
Johnson & Johnson
Ghent University
Kenya National Public Health Institute
University of Washington
Ivo de Carneri Foundation
World Health Organization
London School of Hygiene and Tropical Medicine
RTI International
Johns Hopkins University

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Soil-transmitted helminthiasis (STH) is caused by intestinal parasites that require an obligate development period in the soil [1,2], predominantly roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), and hookworms (Ancylostoma duodenale and Necator americanus), with the recent addition of threadworm (Strongyloides stercoralis). Historically, these parasites have been among the most common infections in humans, disproportionately affecting the world’s most disadvantaged and marginalized people.

Original language	English
Article number	e0012521
Pages (from-to)	e0012521
Journal	PLoS Neglected Tropical Diseases
Volume	18
Issue number	10
DOIs	https://doi.org/10.1371/journal.pntd.0012521
Publication status	Published - 21 Oct 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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PntdFinal published version, 365 KBLicence: CC0

Cite this

Emerson, P. M., Evans, D., Freeman, M. C., Hanson, C., Kalua, K., Keiser, J., Krolewiecki, A., Leonard, L., Levecke, B., Matendechero, S., Means, A. R., Montresor, A., Mupfasoni, D., Pullan, R. L., Rotondo, L. A., Stephens, M., Sullivan, K. M., Walson, J. L., Williams, T., & Utzinger, J. (2024). Need for a paradigm shift in soil-transmitted helminthiasis control: Targeting the right people, in the right place, and with the right drug(s). PLoS Neglected Tropical Diseases, 18(10), e0012521. Article e0012521. https://doi.org/10.1371/journal.pntd.0012521

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abstract = "Soil-transmitted helminthiasis (STH) is caused by intestinal parasites that require an obligate development period in the soil [1,2], predominantly roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), and hookworms (Ancylostoma duodenale and Necator americanus), with the recent addition of threadworm (Strongyloides stercoralis). Historically, these parasites have been among the most common infections in humans, disproportionately affecting the world{\textquoteright}s most disadvantaged and marginalized people.",

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Emerson, PM, Evans, D, Freeman, MC, Hanson, C, Kalua, K, Keiser, J, Krolewiecki, A, Leonard, L, Levecke, B, Matendechero, S, Means, AR, Montresor, A, Mupfasoni, D, Pullan, RL, Rotondo, LA, Stephens, M, Sullivan, KM, Walson, JL, Williams, T & Utzinger, J 2024, 'Need for a paradigm shift in soil-transmitted helminthiasis control: Targeting the right people, in the right place, and with the right drug(s)', PLoS Neglected Tropical Diseases, vol. 18, no. 10, e0012521, pp. e0012521. https://doi.org/10.1371/journal.pntd.0012521

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AU - Emerson, Paul M.

AU - Evans, Darin

AU - Freeman, Matthew C.

AU - Hanson, Christy

AU - Kalua, Khumbo

AU - Keiser, Jennifer

AU - Krolewiecki, Alejandro

AU - Leonard, Lynn

AU - Levecke, Bruno

AU - Matendechero, Sultani

AU - Means, Arianna Rubin

AU - Montresor, Antonio

AU - Mupfasoni, Denise

AU - Pullan, Rachel L.

AU - Rotondo, Lisa A.

AU - Stephens, Mariana

AU - Sullivan, Kristin M.

AU - Walson, Judd L.

AU - Williams, Tijana

AU - Utzinger, Jürg

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AB - Soil-transmitted helminthiasis (STH) is caused by intestinal parasites that require an obligate development period in the soil [1,2], predominantly roundworm (Ascaris lumbricoides), whipworm (Trichuris trichiura), and hookworms (Ancylostoma duodenale and Necator americanus), with the recent addition of threadworm (Strongyloides stercoralis). Historically, these parasites have been among the most common infections in humans, disproportionately affecting the world’s most disadvantaged and marginalized people.

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DO - 10.1371/journal.pntd.0012521

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M1 - e0012521

ER -

Need for a paradigm shift in soil-transmitted helminthiasis control: Targeting the right people, in the right place, and with the right drug(s)

Abstract

UN SDGs

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