Mosquito carboxylesterases: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism

Janet Hemingway; S. H.P.P. Karunaratne

doi:10.1046/j.1365-2915.1998.00082.x

Mosquito carboxylesterases: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism

Janet Hemingway, S. H.P.P. Karunaratne

Research output: Contribution to journal › Review article › peer-review

269 Citations (Scopus)

Abstract

The major mechanism of organophosphorus insecticide resistance in Culex mosquitoes involves the elevation of one or more esterases. The general mechanism underlying this resistance is the amplification of the structural genes. This review covers the classification of the mosquito esterases in the context of classical esterase nomenclature. The function of the amplified esterases and the structure of the amplified DNA on which they occur are also described. Implications of information on the esterase amplicons are discussed in relation to the evolution and migration of insecticide resistance in Culex.

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	Medical and Veterinary Entomology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1046/j.1365-2915.1998.00082.x
Publication status	Published - 1 Jan 1998
Externally published	Yes

Keywords

Carbamate
Carboxylesterase
Culex
Culicidae
Esterase
Insecticide resistance
Mosquitoes
Organophosphorus insecticides

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10.1046/j.1365-2915.1998.00082.x

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title = "Mosquito carboxylesterases: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism",

abstract = "The major mechanism of organophosphorus insecticide resistance in Culex mosquitoes involves the elevation of one or more esterases. The general mechanism underlying this resistance is the amplification of the structural genes. This review covers the classification of the mosquito esterases in the context of classical esterase nomenclature. The function of the amplified esterases and the structure of the amplified DNA on which they occur are also described. Implications of information on the esterase amplicons are discussed in relation to the evolution and migration of insecticide resistance in Culex.",

keywords = "Carbamate, Carboxylesterase, Culex, Culicidae, Esterase, Insecticide resistance, Mosquitoes, Organophosphorus insecticides",

author = "Janet Hemingway and Karunaratne, \{S. H.P.P.\}",

year = "1998",

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Hemingway, J & Karunaratne, SHPP 1998, 'Mosquito carboxylesterases: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism', Medical and Veterinary Entomology, vol. 12, no. 1, pp. 1-12. https://doi.org/10.1046/j.1365-2915.1998.00082.x

Mosquito carboxylesterases: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism. / Hemingway, Janet; Karunaratne, S. H.P.P.
In: Medical and Veterinary Entomology, Vol. 12, No. 1, 01.01.1998, p. 1-12.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Mosquito carboxylesterases: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism: A review of the molecular biology and biochemistry of a major insecticide resistance mechanism

AU - Hemingway, Janet

AU - Karunaratne, S. H.P.P.

PY - 1998/1/1

Y1 - 1998/1/1

N2 - The major mechanism of organophosphorus insecticide resistance in Culex mosquitoes involves the elevation of one or more esterases. The general mechanism underlying this resistance is the amplification of the structural genes. This review covers the classification of the mosquito esterases in the context of classical esterase nomenclature. The function of the amplified esterases and the structure of the amplified DNA on which they occur are also described. Implications of information on the esterase amplicons are discussed in relation to the evolution and migration of insecticide resistance in Culex.

AB - The major mechanism of organophosphorus insecticide resistance in Culex mosquitoes involves the elevation of one or more esterases. The general mechanism underlying this resistance is the amplification of the structural genes. This review covers the classification of the mosquito esterases in the context of classical esterase nomenclature. The function of the amplified esterases and the structure of the amplified DNA on which they occur are also described. Implications of information on the esterase amplicons are discussed in relation to the evolution and migration of insecticide resistance in Culex.

KW - Carbamate

KW - Carboxylesterase

KW - Culex

KW - Culicidae

KW - Esterase

KW - Insecticide resistance

KW - Mosquitoes

KW - Organophosphorus insecticides

U2 - 10.1046/j.1365-2915.1998.00082.x

DO - 10.1046/j.1365-2915.1998.00082.x

M3 - Review article

SN - 0269-283X

VL - 12

SP - 1

EP - 12

JO - Medical and Veterinary Entomology

JF - Medical and Veterinary Entomology

IS - 1

ER -