Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection.

Elissavet Nikolaou; Annie Blizard; Sherin Pojar; Elena Mitsi; Esther German; Jesus Reine Gutierrez; Helen Hill; Paul S. McNamara; Andrea Collins; Daniela Ferreira; Simon P. Jochems

doi:10.1097/inf.0000000000002454

Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection.

Elissavet Nikolaou
, Annie Blizard
, Sherin Pojar
, Elena Mitsi
, Esther German
, Jesus Reine Gutierrez
, Helen Hill
, Paul S. McNamara
, Andrea Collins
, Daniela Ferreira
, Simon P. Jochems

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Nasopharyngeal colonization of potential respiratory pathogens such as Streptococcus pneumoniae is the major source of transmission and precursor of invasive disease. Swabbing deeply the nasopharynx, which is currently recommended by World Health Organization, provides accurate pneumococcal detection but is unpleasant. We showed that nasal lining fluid filter strips offer equal detection sensitivity.

Original language	English
Pages (from-to)	1147-1149
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	38
Issue number	11
Early online date	1 Oct 2019
DOIs	https://doi.org/10.1097/inf.0000000000002454
Publication status	Published - 1 Nov 2019

Keywords

Children
Colonization
Pneumococcus
Quantitative PCR
Synthetic absorptive matrices

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10.1097/inf.0000000000002454Licence: CC BY

Minimally Invasive Nasal Sampling in ChildrenFinal published version, 349 KBLicence: CC BY
PIDJ Nasosorption sampling Full versionAccepted author manuscript, 42.4 KBLicence: CC BY

The human lung immune responses to nasopharyngeal pneumococcal colonisation in healthy adults
Mitsi, E. (Author), Ferreira, D. (Supervisor), Jochems, S. (Supervisor) & Jambo, K. (Supervisor), 2019
Student thesis: Doctoral thesis

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abstract = "Nasopharyngeal colonization of potential respiratory pathogens such as Streptococcus pneumoniae is the major source of transmission and precursor of invasive disease. Swabbing deeply the nasopharynx, which is currently recommended by World Health Organization, provides accurate pneumococcal detection but is unpleasant. We showed that nasal lining fluid filter strips offer equal detection sensitivity.",

keywords = "Children, Colonization, Pneumococcus, Quantitative PCR, Synthetic absorptive matrices",

author = "Elissavet Nikolaou and Annie Blizard and Sherin Pojar and Elena Mitsi and Esther German and \{Reine Gutierrez\}, Jesus and Helen Hill and McNamara, \{Paul S.\} and Andrea Collins and Daniela Ferreira and Jochems, \{Simon P.\}",

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AU - Nikolaou, Elissavet

AU - Blizard, Annie

AU - Pojar, Sherin

AU - Mitsi, Elena

AU - German, Esther

AU - Reine Gutierrez, Jesus

AU - Hill, Helen

AU - McNamara, Paul S.

AU - Collins, Andrea

AU - Ferreira, Daniela

AU - Jochems, Simon P.

PY - 2019/11/1

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AB - Nasopharyngeal colonization of potential respiratory pathogens such as Streptococcus pneumoniae is the major source of transmission and precursor of invasive disease. Swabbing deeply the nasopharynx, which is currently recommended by World Health Organization, provides accurate pneumococcal detection but is unpleasant. We showed that nasal lining fluid filter strips offer equal detection sensitivity.

KW - Children

KW - Colonization

KW - Pneumococcus

KW - Quantitative PCR

KW - Synthetic absorptive matrices

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DO - 10.1097/inf.0000000000002454

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JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

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Minimally Invasive Nasal Sampling in Children Offers Accurate Pneumococcal Colonization Detection.

Abstract

Keywords

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Student theses

The human lung immune responses to nasopharyngeal pneumococcal colonisation in healthy adults

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