Abstract
Mycobacterium tuberculosis is an expert and deadly pathogen, causing the disease tuberculosis (TB) in humans. It has several notable features: the ability to enter non-replicating states for long periods and cause latent infection; metabolic remodelling during chronic infection; a thick, waxy cell wall; slow growth rate in culture; and intrinsic drug resistance and antibiotic tolerance. As a pathogen, M. tuberculosis has a complex relationship with its host, is able to replicate inside macrophages, and expresses diverse immunomodulatory molecules. M. tuberculosis currently causes over 1.8 million deaths a year, making it the world’s most deadly human pathogen.
| Original language | English |
|---|---|
| Pages (from-to) | 437-439 |
| Number of pages | 3 |
| Journal | Microbiology (United Kingdom) |
| Volume | 164 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 2018 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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