Methods of SARS-CoV-2 Inactivation.

Enya Anderson, Tessa Prince, Lance Turtle, Grant Hughes, Ian Patterson

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Citations (Scopus)

Abstract

Inactivation methods allow for hazard group 3 (HG3) pathogens to be disposed of and used safely in downstream experiments and assays to be carried out at lower containment levels. Commonly used viral inactivation methods include heat inactivation, fixation methods, ultraviolet (UV) light and detergent inactivation. Here we describe known methods used to inactivate SARS-CoV-2 for safe downstream biological assays. [Abstract copyright: © 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.]

Original languageEnglish
Title of host publicationMethods in molecular biology (Clifton, N.J.)
PublisherHumana
Pages465-473
Number of pages9
DOIs
Publication statusPublished - 14 May 2022

Keywords

  • Assay
  • Inactivation
  • SARS-CoV-2
  • TRIzol
  • UV
  • Vero

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