TY - JOUR
T1 - Long-lasting insecticide-treated house screens and targeted treatment of productive breeding-sites for dengue vector control in Acapulco, Mexico
AU - Che-Mendoza, Azael
AU - Guillermo-May, Guillermo
AU - Herrera-Bojórquez, Josué
AU - Barrera-Pérez, Mario
AU - Dzul-Manzanilla, Felipe
AU - Gutierrez-Castro, Cipriano
AU - Arredondo-Jiménez, Juan I.
AU - Sánchez-Tejeda, Gustavo
AU - Vazquez-Prokopec, Gonzalo
AU - Ranson, Hilary
AU - Lenhart, Audrey
AU - Sommerfeld, Johannes
AU - McCall, Philip
AU - Kroeger, Axel
AU - Manrique-Saide, Pablo
PY - 2015/2/1
Y1 - 2015/2/1
N2 - Background Long-lasting insecticidal net screens (LLIS) fitted to domestic windows and doors in combination with targeted treatment (TT) of the most productive Aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in Mexico between 2011 and 2013.Methods Sequentially over 2 years, LLIS and TT were deployed in 10 treatment clusters (100 houses/cluster) and followed up over 24 months. Cross-sectional surveys quantified infestations of adult mosquitoes, immature stages at baseline (pre-intervention) and in four post-intervention samples at 6-monthly intervals. Identical surveys were carried out in 10 control clusters that received no treatment.Results LLIS clusters had significantly lower infestations compared to control clusters at 5 and 12 months after installation, as measured by adult (male and female) and pupal-based vector indices. After addition of TT to the intervention houses in intervention clusters, indices remained significantly lower in the treated clusters until 18 (immature and adult stage indices) and 24 months (adult indices only) post-intervention.Conclusions These safe, simple affordable vector control tools were well-accepted by study participants and are potentially suitable in many regions at risk from dengue worldwide.
AB - Background Long-lasting insecticidal net screens (LLIS) fitted to domestic windows and doors in combination with targeted treatment (TT) of the most productive Aedes aegypti breeding sites were evaluated for their impact on dengue vector indices in a cluster-randomised trial in Mexico between 2011 and 2013.Methods Sequentially over 2 years, LLIS and TT were deployed in 10 treatment clusters (100 houses/cluster) and followed up over 24 months. Cross-sectional surveys quantified infestations of adult mosquitoes, immature stages at baseline (pre-intervention) and in four post-intervention samples at 6-monthly intervals. Identical surveys were carried out in 10 control clusters that received no treatment.Results LLIS clusters had significantly lower infestations compared to control clusters at 5 and 12 months after installation, as measured by adult (male and female) and pupal-based vector indices. After addition of TT to the intervention houses in intervention clusters, indices remained significantly lower in the treated clusters until 18 (immature and adult stage indices) and 24 months (adult indices only) post-intervention.Conclusions These safe, simple affordable vector control tools were well-accepted by study participants and are potentially suitable in many regions at risk from dengue worldwide.
KW - Aedes aegypti
KW - Control
KW - Dengue
KW - LLIS
KW - Mexico
KW - Targeted treatment
U2 - 10.1093/trstmh/tru189
DO - 10.1093/trstmh/tru189
M3 - Article
SN - 0035-9203
VL - 109
SP - 106
EP - 115
JO - Transactions of the Royal Society of Tropical Medicine and Hygiene
JF - Transactions of the Royal Society of Tropical Medicine and Hygiene
IS - 2
ER -
