Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service

Becky Nightingale; Nneka Nwosu; Farheen Kutubudin; Tom Fletcher; Joe Lewis; Frederick Frost; Kathryn Haigh; Ryan Robinson; Ayesha Kumar; Gareth Jones; Deborah Brown; Michael Abouyannis; Mike Beadsworth; Peter Hampshire; Stephen Aston; Manish Gautam; Hassan Burhan

doi:10.1136/bmjresp-2020-000639

Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service

Becky Nightingale
, Nneka Nwosu
, Farheen Kutubudin
, Tom Fletcher
, Joe Lewis
, Frederick Frost
, Kathryn Haigh
, Ryan Robinson
, Ayesha Kumar
, Gareth Jones
, Deborah Brown
, Michael Abouyannis
, Mike Beadsworth
, Peter Hampshire
, Stephen Aston
, Manish Gautam
, Hassan Burhan

Research output: Contribution to journal › Review article › peer-review

60 Citations (Scopus)

Abstract

The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58%) avoided mechanical ventilation and a total of 19 out of 24 (79%) have survived and been discharged from our care.

Original language	English
Article number	e000639
Pages (from-to)	e000639
Journal	BMJ Open Respiratory Research
Volume	7
Issue number	1
DOIs	https://doi.org/10.1136/bmjresp-2020-000639
Publication status	Published - 5 Jul 2020

Keywords

non invasive ventilation
respiratory Infection

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1136/bmjresp-2020-000639Licence: CC BY-NC

COVID 19Final published version, 224 KBLicence: CC BY-NC

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Nightingale, B., Nwosu, N., Kutubudin, F., Fletcher, T., Lewis, J., Frost, F., Haigh, K., Robinson, R., Kumar, A., Jones, G., Brown, D., Abouyannis, M., Beadsworth, M., Hampshire, P., Aston, S., Gautam, M., & Burhan, H. (2020). Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service. BMJ Open Respiratory Research, 7(1), e000639. Article e000639. https://doi.org/10.1136/bmjresp-2020-000639

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abstract = "The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58\%) avoided mechanical ventilation and a total of 19 out of 24 (79\%) have survived and been discharged from our care.",

keywords = "non invasive ventilation, respiratory Infection",

author = "Becky Nightingale and Nneka Nwosu and Farheen Kutubudin and Tom Fletcher and Joe Lewis and Frederick Frost and Kathryn Haigh and Ryan Robinson and Ayesha Kumar and Gareth Jones and Deborah Brown and Michael Abouyannis and Mike Beadsworth and Peter Hampshire and Stephen Aston and Manish Gautam and Hassan Burhan",

year = "2020",

month = jul,

day = "5",

doi = "10.1136/bmjresp-2020-000639",

language = "English",

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pages = "e000639",

journal = "BMJ Open Respiratory Research",

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Nightingale, B, Nwosu, N, Kutubudin, F, Fletcher, T , Lewis, J, Frost, F, Haigh, K, Robinson, R, Kumar, A, Jones, G, Brown, D, Abouyannis, M, Beadsworth, M, Hampshire, P, Aston, S, Gautam, M & Burhan, H 2020, 'Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service', BMJ Open Respiratory Research, vol. 7, no. 1, e000639, pp. e000639. https://doi.org/10.1136/bmjresp-2020-000639

Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service. / Nightingale, Becky; Nwosu, Nneka; Kutubudin, Farheen et al.
In: BMJ Open Respiratory Research, Vol. 7, No. 1, e000639, 05.07.2020, p. e000639.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service

AU - Nightingale, Becky

AU - Nwosu, Nneka

AU - Kutubudin, Farheen

AU - Fletcher, Tom

AU - Lewis, Joe

AU - Frost, Frederick

AU - Haigh, Kathryn

AU - Robinson, Ryan

AU - Kumar, Ayesha

AU - Jones, Gareth

AU - Brown, Deborah

AU - Abouyannis, Michael

AU - Beadsworth, Mike

AU - Hampshire, Peter

AU - Aston, Stephen

AU - Gautam, Manish

AU - Burhan, Hassan

PY - 2020/7/5

Y1 - 2020/7/5

N2 - The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58%) avoided mechanical ventilation and a total of 19 out of 24 (79%) have survived and been discharged from our care.

AB - The aim of this case series is to describe and evaluate our experience of continuous positive airway pressure (CPAP) to treat type 1 respiratory failure in patients with COVID-19. CPAP was delivered in negative pressure rooms in the newly repurposed infectious disease unit. We report a cohort of 24 patients with type 1 respiratory failure and COVID-19 admitted to the Royal Liverpool Hospital between 1 April and 30 April 2020. Overall, our results were positive; we were able to safely administer CPAP outside the walls of a critical care or high dependency unit environment and over half of patients (58%) avoided mechanical ventilation and a total of 19 out of 24 (79%) have survived and been discharged from our care.

KW - non invasive ventilation

KW - respiratory Infection

U2 - 10.1136/bmjresp-2020-000639

DO - 10.1136/bmjresp-2020-000639

M3 - Review article

SN - 2052-4439

VL - 7

SP - e000639

JO - BMJ Open Respiratory Research

JF - BMJ Open Respiratory Research

IS - 1

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ER -

Is continuous positive airway pressure (CPAP) a new standard of care for type 1 respiratory failure in COVID-19 patients? A retrospective observational study of a dedicated COVID-19 CPAP service

Abstract

Keywords

UN SDGs

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