Investigation of neonatal brain cytochrome redox by NIRS

Y. A.B.D. Wickramasinghe, P. Rolfe, K. Palmer, Stephen Spencer

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Near Infrared Spectroscopy (NIRS) has been used to detect changes in cerebral blood and tissue oxygenation. Redox state of enzyme cytochrome aa3 (Cyt aa3) is thought to give an indication of tissue oxygenation. This information would be of value in exploring the aetiology of cerebral ischaemic lesions in preterm infants. However we have found that the change in cerebral cytochrome redox in infants following desaturation was inconsistent and insignificant.
Original languageEnglish
Pages (from-to)307-308
Number of pages2
JournalDevelopmental Brain Research
Volume89
Issue number2
DOIs
Publication statusPublished - 21 Nov 1995
Externally publishedYes

Keywords

  • Near infrared spectroscopy
  • Neonatal brain cytochrome redox

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