Interoperability of Statistical Models in Pandemic Preparedness: Principles and Reality: Principles and Reality

George Nicholson, Marta Blangiardo, Mark Briers, Peter Diggle, Tor Erlend Fjelde, Hong Ge, Robert J.B. Goudie, Radka Jersakova, Ruairidh E. King, Brieuc C.L. Lehmann, Ann Marie Mallon, Tullia Padellini, Yee Whye Teh, Chris Holmes, Sylvia Richardson

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

We present interoperability as a guiding framework for statistical modelling to assist policy makers asking multiple questions using diverse datasets in the face of an evolving pandemic response. Interoperability provides an important set of principles for future pandemic preparedness, through the joint design and deployment of adaptable systems of statistical models for disease surveillance using probabilistic reasoning. We illustrate this through case studies for inferring and characterising spatial-temporal prevalence and reproduction numbers of SARS-CoV-2 infections in England.
Original languageEnglish
Pages (from-to)183-206
Number of pages24
JournalStatistical Science
Volume37
Issue number2
DOIs
Publication statusPublished - 1 May 2022
Externally publishedYes

Keywords

  • Bayesian graphical models
  • Bayesian melding
  • Covid-19
  • Evidence synthesis
  • Interoperability
  • Modularization
  • Multisource inference

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