Increase in susceptibility of young adults to hepatitis B infection in the Republic of Yemen

Talal A. Sallam; Luis Cuevas; C. Y. William Tong

doi:10.1016/s0035-9203(03)90151-9

Increase in susceptibility of young adults to hepatitis B infection in the Republic of Yemen

Talal A. Sallam, Luis Cuevas, C. Y. William Tong

Clinical Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Susceptibility to hepatitis B virus (HBV) infection among 987 young adult male blood donors in 2 major Yemeni cities was investigated. Hepatitis B surface antigen (HBsAg) was detected in 10.8% (107/987) of donors and 284 (28.8%) had evidence of ongoing or past HBV infection. Hepatitis B surface antibody (anti-HBs) only was detected in 34 (3.4%) donors. Thus, 67.8% (669/987) of donors had no detectable HBV-markers indicating susceptibility to infection. The proportion of HBV-susceptible donors decreased from 70.9% (249/351) in donors aged < 25 years to 69.4% (334/481) in those aged 25-34 years and 55.5% (86/155) in donors aged > 34 years (P = 0.002). The high proportion of susceptible young adults in a community with a high HBsAg carrier rate could be the result of changing epidemiology of hepatitis B in Yemen. Consideration should therefore be given to immunizing young adults as an adjunct to the current expanded infant immunization programme.

Original language	English
Pages (from-to)	302-304
Number of pages	3
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	97
Issue number	3
DOIs	https://doi.org/10.1016/s0035-9203(03)90151-9
Publication status	Published - 1 Jun 2003

Keywords

Hepatitis B virus
Seroprevalence
Yemen

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/s0035-9203(03)90151-9

Cite this

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title = "Increase in susceptibility of young adults to hepatitis B infection in the Republic of Yemen",

abstract = "Susceptibility to hepatitis B virus (HBV) infection among 987 young adult male blood donors in 2 major Yemeni cities was investigated. Hepatitis B surface antigen (HBsAg) was detected in 10.8% (107/987) of donors and 284 (28.8%) had evidence of ongoing or past HBV infection. Hepatitis B surface antibody (anti-HBs) only was detected in 34 (3.4%) donors. Thus, 67.8% (669/987) of donors had no detectable HBV-markers indicating susceptibility to infection. The proportion of HBV-susceptible donors decreased from 70.9% (249/351) in donors aged < 25 years to 69.4% (334/481) in those aged 25-34 years and 55.5% (86/155) in donors aged > 34 years (P = 0.002). The high proportion of susceptible young adults in a community with a high HBsAg carrier rate could be the result of changing epidemiology of hepatitis B in Yemen. Consideration should therefore be given to immunizing young adults as an adjunct to the current expanded infant immunization programme.",

keywords = "Hepatitis B virus, Seroprevalence, Yemen",

author = "Sallam, {Talal A.} and Luis Cuevas and {William Tong}, {C. Y.}",

year = "2003",

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TY - JOUR

T1 - Increase in susceptibility of young adults to hepatitis B infection in the Republic of Yemen

AU - Sallam, Talal A.

AU - Cuevas, Luis

AU - William Tong, C. Y.

PY - 2003/6/1

Y1 - 2003/6/1

N2 - Susceptibility to hepatitis B virus (HBV) infection among 987 young adult male blood donors in 2 major Yemeni cities was investigated. Hepatitis B surface antigen (HBsAg) was detected in 10.8% (107/987) of donors and 284 (28.8%) had evidence of ongoing or past HBV infection. Hepatitis B surface antibody (anti-HBs) only was detected in 34 (3.4%) donors. Thus, 67.8% (669/987) of donors had no detectable HBV-markers indicating susceptibility to infection. The proportion of HBV-susceptible donors decreased from 70.9% (249/351) in donors aged < 25 years to 69.4% (334/481) in those aged 25-34 years and 55.5% (86/155) in donors aged > 34 years (P = 0.002). The high proportion of susceptible young adults in a community with a high HBsAg carrier rate could be the result of changing epidemiology of hepatitis B in Yemen. Consideration should therefore be given to immunizing young adults as an adjunct to the current expanded infant immunization programme.

AB - Susceptibility to hepatitis B virus (HBV) infection among 987 young adult male blood donors in 2 major Yemeni cities was investigated. Hepatitis B surface antigen (HBsAg) was detected in 10.8% (107/987) of donors and 284 (28.8%) had evidence of ongoing or past HBV infection. Hepatitis B surface antibody (anti-HBs) only was detected in 34 (3.4%) donors. Thus, 67.8% (669/987) of donors had no detectable HBV-markers indicating susceptibility to infection. The proportion of HBV-susceptible donors decreased from 70.9% (249/351) in donors aged < 25 years to 69.4% (334/481) in those aged 25-34 years and 55.5% (86/155) in donors aged > 34 years (P = 0.002). The high proportion of susceptible young adults in a community with a high HBsAg carrier rate could be the result of changing epidemiology of hepatitis B in Yemen. Consideration should therefore be given to immunizing young adults as an adjunct to the current expanded infant immunization programme.

KW - Hepatitis B virus

KW - Seroprevalence

KW - Yemen

U2 - 10.1016/s0035-9203(03)90151-9

DO - 10.1016/s0035-9203(03)90151-9

M3 - Article

SN - 0035-9203

VL - 97

SP - 302

EP - 304

JO - Transactions of the Royal Society of Tropical Medicine and Hygiene

JF - Transactions of the Royal Society of Tropical Medicine and Hygiene

IS - 3

ER -

Increase in susceptibility of young adults to hepatitis B infection in the Republic of Yemen

Abstract

Keywords

UN SDGs

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