In routine UK hospital practice T-SPOT.TB™ is useful in some patients with a modest pre-test probability of active tuberculosis.

Lance Turtle, Tim Kemp, Geraint R. Davies, Bertie Squire, Nicholas Beeching, Michael B.J. Beadsworth

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Although it can add weight to a clinical diagnosis, T-SPOT.TB™ assay is not reliable for the diagnosis of active tuberculosis in a real world setting where the test is often used in patients with smear negative or extra-pulmonary disease. The test is useful for ruling out disease in HIV negative patients.

Original languageEnglish
Pages (from-to)363-367
Number of pages5
JournalEuropean Journal of Internal Medicine
Volume23
Issue number4
DOIs
Publication statusPublished - 1 Jun 2012
Externally publishedYes

Keywords

  • ELISpot
  • Interferon-gamma release assay
  • Sensitivity and specificity
  • Tuberculosis

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