Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format

Alonso Carrasco-Labra, Romina Brignardello-Petersen, Nancy Santesso, Ignacio Neumann, Reem A. Mustafa, Lawrence Mbuagbaw, Itziar Etxeandia Ikobaltzeta, Catherine De Stio, Lauren J. McCullagh, Pablo Alonso-Coello, Joerg J. Meerpohl, Per Olav Vandvik, Jan L. Brozek, Elie A. Akl, Patrick Bossuyt, Rachel Churchill, Claire Glenton, Sarah Rosenbaum, Peter Tugwell, Vivian WelchPaul Garner, Gordon Guyatt, Holger J. Schünemann

Research output: Contribution to journalArticlepeer-review

103 Citations (Scopus)

Abstract

Objectives

The current format of summary of findings (SoFs) tables for presenting effect estimates and associated quality of evidence improve understanding and assist users finding key information in systematic reviews. Users of SoF tables have demanded alternative formats to express findings from systematic reviews.

Study Design and Setting

We conducted a randomized controlled trial among systematic review users to compare the relative merits of a new format with the current formats of SoF tables regarding understanding, accessibility of information, satisfaction, and preference. Our primary goal was to show that the new format is not inferior to the current format.

Results

Of 390 potentially eligible subjects, 290 were randomized. Of seven items testing understanding, three showed similar results, two showed small differences favoring the new format, and two (understanding risk difference and quality of the evidence associated with a treatment effect) showed large differences favoring the new format [63% (95% confidence interval {CI}: 55, 71) and 62% (95% CI: 52, 71) more correct answers, respectively]. Respondents rated information in the alternative format as more accessible overall and preferred the new format over the current format.

Conclusions

While providing at least similar levels of understanding for some items and increased understanding for others, users prefer the new format of SoF tables

Original languageEnglish
Pages (from-to)7-18
Number of pages12
JournalJournal of Clinical Epidemiology
Volume74
DOIs
Publication statusPublished - 11 Jan 2016

Keywords

  • Evidence summaries
  • Evidence tables
  • Formatting
  • GRADE
  • GRADEpro
  • Guidelines
  • Summary of findings table
  • Systematic reviews
  • Understanding

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