How do musculoskeletal disorders impact on quality of life in Tanzania? Results from a community-based survey

  • Eleanor Grieve
  • , Manuela Deidda
  • , Stefanie J. Krauth
  • , Sanjura Mandela Biswaro
  • , Jo E.B. Halliday
  • , Ping Hsuan Hsieh
  • , Clive Kelly
  • , Kajiru Kilonzo
  • , Kiula P. Kiula
  • , Rose Kolimba
  • , Elizabeth F. Msoka
  • , Stefan Siebert
  • , Richard Walker
  • , Nateiya Mmeta Yongolo
  • , Blandina Mmbaga
  • , Emma McIntosh

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives There are little available data on the prevalence, economic and quality of life impacts of musculoskeletal disorders in sub-Saharan Africa. This lack of evidence is wholly disproportionate to the significant disability burden of musculoskeletal disorders as reported in high-income countries. Our research aimed to undertake an adequately powered study to identify, measure and value the health impact of musculoskeletal conditions in the Kilimanjaro region, Tanzania. 

Design A community-based cross-sectional survey was undertaken between January 2021 and September 2021. A two-stage cluster sampling with replacement and probability proportional to size was used to select a representative sample of the population. 

Setting The survey was conducted in 15 villages in the Hai District, Kilimanjaro region, Tanzania. Participants Economic and health-related quality of life (HRQOL) questionnaires were administered to a sample of residents (aged over 5 years old) in selected households (N=1050). There were a total of 594 respondents, of whom 153 had a confirmed musculoskeletal disorder and 441 matched controls. Almost three-quarters of those identified as having a musculoskeletal disorder were female and had an average age of 66 years. 

Primary and secondary outcome measures Questions on healthcare resource use, expenditure and quality of life were administered to all participants, with additional more detailed economic and quality of life questions administered to those who screened positive, indicating probable arthritis. 

Results There is a statistically significant reduction in HRQOL, on average 25% from a utility score of 0.862 (0.837, 0.886) to 0.636 (0.580, 0.692) for those identified as having a musculoskeletal disorder compared with those without. The attributes 'pain' and 'discomfort' were the major contributors to this reduction in HRQOL. 

Conclusions This research has revealed a significant impact of musculoskeletal conditions on HRQOL in the Hai district in Tanzania. The evidence will be used to guide clinical health practices, interventions design, service provisions and health promotion and awareness activities at institutional, regional and national levels.

Original languageEnglish
Article numbere092877
JournalBMJ Open
Volume15
Issue number12
DOIs
Publication statusPublished - 2 Dec 2025

Keywords

  • Cross-Sectional Studies
  • HEALTH ECONOMICS
  • Musculoskeletal disorders
  • Quality of Life

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