HIV and schistosomiasis co-infection in African children

Amaya Bustinduy; Charles King; Janet Scott; Sarah Appleton; José Carlos Sousa-Figueiredo; Martha Betson; Russell Stothard

doi:10.1016/s1473-3099(14)70001-5

HIV and schistosomiasis co-infection in African children

Amaya Bustinduy, Charles King, Janet Scott, Sarah Appleton, José Carlos Sousa-Figueiredo, Martha Betson, Russell Stothard

Tropical Disease Biology

Research output: Contribution to journal › Review article › peer-review

45 Citations (Scopus)

Abstract

HIV/AIDS and schistosomiasis both cause a substantial disease burden in sub-Saharan Africa and the two diseases often overlap in their epidemiological characteristics. Although disease-specific control interventions are continuing, potential synergies in the control efforts for these two diseases have not been investigated. With a focus on children with schistosomiasis, we assess the risk for increased HIV transmission, HIV progression, and impaired response to drugs when given alongside HIV interventions. A new research agenda tailored to children is needed to better understand the interactions of these two diseases and the potential for combined responses.

Original language	English
Pages (from-to)	640-649
Number of pages	10
Journal	The Lancet Infectious Diseases
Volume	14
Issue number	7
DOIs	https://doi.org/10.1016/s1473-3099(14)70001-5
Publication status	Published - 1 Jul 2014

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AU - Bustinduy, Amaya

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AU - Scott, Janet

AU - Appleton, Sarah

AU - Sousa-Figueiredo, José Carlos

AU - Betson, Martha

AU - Stothard, Russell

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AB - HIV/AIDS and schistosomiasis both cause a substantial disease burden in sub-Saharan Africa and the two diseases often overlap in their epidemiological characteristics. Although disease-specific control interventions are continuing, potential synergies in the control efforts for these two diseases have not been investigated. With a focus on children with schistosomiasis, we assess the risk for increased HIV transmission, HIV progression, and impaired response to drugs when given alongside HIV interventions. A new research agenda tailored to children is needed to better understand the interactions of these two diseases and the potential for combined responses.

U2 - 10.1016/s1473-3099(14)70001-5

DO - 10.1016/s1473-3099(14)70001-5

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JF - The Lancet Infectious Diseases

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ER -

HIV and schistosomiasis co-infection in African children

Abstract

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