TY - JOUR
T1 - HIV-1/AIDS and the control of other infectious diseases in Africa
AU - Corbett, Elizabeth L.
AU - Steketee, Richard W.
AU - Ter Kuile, Feiko
AU - Latif, Ahmed S.
AU - Kamali, Anatoli
AU - Hayes, Richard J.
PY - 2002/6/22
Y1 - 2002/6/22
N2 - The effect of HIV-1 on other infectious diseases in Africa is an increasing public health concern. In this review, we describe the role that three major infectious diseases - malaria, sexually transmitted diseases (STDs), and tuberculosis - have had in the HIV-1 epidemic. The high prevalence of untreated STD infections has been a major factor facilitating the spread of HIV-1 in Africa; with the synergistic interaction between HIV-1 transmission and genital herpes being of especial concern for control of both diseases. Increased susceptibility to tuberculosis after infection with HIV-1 has led to a rising incidence and threat of increased transmission of tuberculosis. Clinical malaria occurs with an increased frequency and severity in HIV-1-infected individuals, especially during pregnancy. As with tuberculosis, STDs, and other communicable HIV-1-associated diseases, the net effect of HIV-1 might include increased rates of malaria transmission across communities. In addition to enhancing access to HIV-1 prevention and care, public health surveillance and control programmes should be greatly intensified to cope with the new realities of infectious disease control in Africa.
AB - The effect of HIV-1 on other infectious diseases in Africa is an increasing public health concern. In this review, we describe the role that three major infectious diseases - malaria, sexually transmitted diseases (STDs), and tuberculosis - have had in the HIV-1 epidemic. The high prevalence of untreated STD infections has been a major factor facilitating the spread of HIV-1 in Africa; with the synergistic interaction between HIV-1 transmission and genital herpes being of especial concern for control of both diseases. Increased susceptibility to tuberculosis after infection with HIV-1 has led to a rising incidence and threat of increased transmission of tuberculosis. Clinical malaria occurs with an increased frequency and severity in HIV-1-infected individuals, especially during pregnancy. As with tuberculosis, STDs, and other communicable HIV-1-associated diseases, the net effect of HIV-1 might include increased rates of malaria transmission across communities. In addition to enhancing access to HIV-1 prevention and care, public health surveillance and control programmes should be greatly intensified to cope with the new realities of infectious disease control in Africa.
U2 - 10.1016/s0140-6736(02)09095-5
DO - 10.1016/s0140-6736(02)09095-5
M3 - Review article
SN - 0140-6736
VL - 359
SP - 2177
EP - 2187
JO - The Lancet
JF - The Lancet
IS - 9324
ER -
