Geographically targeted chronic infection screening: lessons from a hepatitis B pilot study in the UK

Angus M. O’Ferrall; Alison MacElhinney-West; Mark S. Bell; Michael P. Haslam; Gemma Walker; Donna Norton; Sean A. Burns; Graham Ferrier; Nicholas J.W. Easom

doi:10.1093/trstmh/trac131

Geographically targeted chronic infection screening: lessons from a hepatitis B pilot study in the UK

Angus M. O’Ferrall, Alison MacElhinney-West, Mark S. Bell, Michael P. Haslam, Gemma Walker, Donna Norton, Sean A. Burns, Graham Ferrier, Nicholas J.W. Easom

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic hepatitis B (CHB) most commonly occurs following infection in early childhood. Prevalence varies markedly around the globe. Country of birth is therefore a strong predictor of CHB risk in adults. We used country of birth census data to predict CHB risk and carry out geographically targeted screening in East Yorkshire, UK. Despite engaging individuals born in high-prevalence countries with testing, we observed lower than expected prevalence in targeted highest-risk areas, which may indicate barriers to testing for people with undiagnosed CHB. Improved strategies for engagement with high-risk groups will be key for viral hepatitis elimination.

Original language	English
Pages (from-to)	403-406
Number of pages	4
Journal	Transactions of the Royal Society of Tropical Medicine and Hygiene
Volume	117
Issue number	6
DOIs	https://doi.org/10.1093/trstmh/trac131
Publication status	Published - 10 Jan 2023
Externally published	Yes

Keywords

geographic information system
hepatitis B
migrant health
screening
secondary prevention

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/trstmh/trac131

Cite this

O’Ferrall, A. M., MacElhinney-West, A., Bell, M. S., Haslam, M. P., Walker, G., Norton, D., Burns, S. A., Ferrier, G., & Easom, N. J. W. (2023). Geographically targeted chronic infection screening: lessons from a hepatitis B pilot study in the UK. Transactions of the Royal Society of Tropical Medicine and Hygiene, 117(6), 403-406. https://doi.org/10.1093/trstmh/trac131

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abstract = "Chronic hepatitis B (CHB) most commonly occurs following infection in early childhood. Prevalence varies markedly around the globe. Country of birth is therefore a strong predictor of CHB risk in adults. We used country of birth census data to predict CHB risk and carry out geographically targeted screening in East Yorkshire, UK. Despite engaging individuals born in high-prevalence countries with testing, we observed lower than expected prevalence in targeted highest-risk areas, which may indicate barriers to testing for people with undiagnosed CHB. Improved strategies for engagement with high-risk groups will be key for viral hepatitis elimination.",

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doi = "10.1093/trstmh/trac131",

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T2 - lessons from a hepatitis B pilot study in the UK

AU - O’Ferrall, Angus M.

AU - MacElhinney-West, Alison

AU - Bell, Mark S.

AU - Haslam, Michael P.

AU - Walker, Gemma

AU - Norton, Donna

AU - Burns, Sean A.

AU - Ferrier, Graham

AU - Easom, Nicholas J.W.

PY - 2023/1/10

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N2 - Chronic hepatitis B (CHB) most commonly occurs following infection in early childhood. Prevalence varies markedly around the globe. Country of birth is therefore a strong predictor of CHB risk in adults. We used country of birth census data to predict CHB risk and carry out geographically targeted screening in East Yorkshire, UK. Despite engaging individuals born in high-prevalence countries with testing, we observed lower than expected prevalence in targeted highest-risk areas, which may indicate barriers to testing for people with undiagnosed CHB. Improved strategies for engagement with high-risk groups will be key for viral hepatitis elimination.

AB - Chronic hepatitis B (CHB) most commonly occurs following infection in early childhood. Prevalence varies markedly around the globe. Country of birth is therefore a strong predictor of CHB risk in adults. We used country of birth census data to predict CHB risk and carry out geographically targeted screening in East Yorkshire, UK. Despite engaging individuals born in high-prevalence countries with testing, we observed lower than expected prevalence in targeted highest-risk areas, which may indicate barriers to testing for people with undiagnosed CHB. Improved strategies for engagement with high-risk groups will be key for viral hepatitis elimination.

KW - geographic information system

KW - hepatitis B

KW - migrant health

KW - screening

KW - secondary prevention

U2 - 10.1093/trstmh/trac131

DO - 10.1093/trstmh/trac131

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AN - SCOPUS:85160970409

SN - 0035-9203

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SP - 403

EP - 406

JO - Transactions of the Royal Society of Tropical Medicine and Hygiene

JF - Transactions of the Royal Society of Tropical Medicine and Hygiene

IS - 6

ER -

Geographically targeted chronic infection screening: lessons from a hepatitis B pilot study in the UK

Abstract

Keywords

UN SDGs

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