Geographical and age-related variation in the activity of some enzymes associated with insecticide detoxification in sandflies (Diptera: Phlebotominae).

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Abstract

The activity of glutathione s-transferase (GST), glucose 6-phosphate dehydrogenase (G6PD), and esterases (EST1, EST2) was measured using microtitre plate assays of laboratory colonised Phlebotomus papatasi originating in Afghanistan, Cyprus, India, Iraq, Saudi Arabia, Spain and Tunisia. The mean enzyme activity of the seven populations was significantly different. Enzyme activity did not vary significantly with age in sandflies, unlike some mosquitoes. A baseline enzyme activity for susceptibility is proposed for P. papatasi.

Original languageEnglish
Pages (from-to)445-451
Number of pages7
JournalParassitologia
Volume33 Suppl
Publication statusPublished - 1 Dec 1991

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