Framework for rapid assessment and adoption of new vector control tools

John Vontas; Sarah Moore; Immo Kleinschmidt; Hilary Ranson; Steve Lindsay; Christian Lengeler; Nicholas Hamon; Tom McLean; Janet Hemingway

doi:10.1016/j.pt.2014.02.005

Framework for rapid assessment and adoption of new vector control tools

John Vontas, Sarah Moore, Immo Kleinschmidt, Hilary Ranson, Steve Lindsay, Christian Lengeler, Nicholas Hamon, Tom McLean, Janet Hemingway

Vector Biology

Research output: Contribution to journal › Review article › peer-review

48 Citations (Scopus)

Abstract

Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) using a framework based on measurements of the vectorial capacity of an insect population to transmit disease. We explore links between indicators of VCT efficacy measurable in small-scale experiments that are relevant to entomological and epidemiological parameters measurable only in large-scale proof-of-concept randomised control trials (RCTs). We hypothesise that once RCTs establish links between entomological and epidemiological indicators then rapid evaluation of new products within the same product category may be conducted through smaller scale experiments without repetition of lengthy and expensive RCTs.

Original language	English
Pages (from-to)	191-204
Number of pages	14
Journal	Trends In Parasitology
Volume	30
Issue number	4
DOIs	https://doi.org/10.1016/j.pt.2014.02.005
Publication status	Published - 1 Apr 2014

Keywords

Efficacy
Entomological parameters
Vector control tool
Vectorial capacity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.pt.2014.02.005

Cite this

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title = "Framework for rapid assessment and adoption of new vector control tools",

abstract = "Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) using a framework based on measurements of the vectorial capacity of an insect population to transmit disease. We explore links between indicators of VCT efficacy measurable in small-scale experiments that are relevant to entomological and epidemiological parameters measurable only in large-scale proof-of-concept randomised control trials (RCTs). We hypothesise that once RCTs establish links between entomological and epidemiological indicators then rapid evaluation of new products within the same product category may be conducted through smaller scale experiments without repetition of lengthy and expensive RCTs.",

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AU - Vontas, John

AU - Moore, Sarah

AU - Kleinschmidt, Immo

AU - Ranson, Hilary

AU - Lindsay, Steve

AU - Lengeler, Christian

AU - Hamon, Nicholas

AU - McLean, Tom

AU - Hemingway, Janet

PY - 2014/4/1

Y1 - 2014/4/1

N2 - Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) using a framework based on measurements of the vectorial capacity of an insect population to transmit disease. We explore links between indicators of VCT efficacy measurable in small-scale experiments that are relevant to entomological and epidemiological parameters measurable only in large-scale proof-of-concept randomised control trials (RCTs). We hypothesise that once RCTs establish links between entomological and epidemiological indicators then rapid evaluation of new products within the same product category may be conducted through smaller scale experiments without repetition of lengthy and expensive RCTs.

AB - Evidence-informed health policy making is reliant on systematic access to, and appraisal of, the best available research evidence. This review suggests a strategy to improve the speed at which evidence is gathered on new vector control tools (VCTs) using a framework based on measurements of the vectorial capacity of an insect population to transmit disease. We explore links between indicators of VCT efficacy measurable in small-scale experiments that are relevant to entomological and epidemiological parameters measurable only in large-scale proof-of-concept randomised control trials (RCTs). We hypothesise that once RCTs establish links between entomological and epidemiological indicators then rapid evaluation of new products within the same product category may be conducted through smaller scale experiments without repetition of lengthy and expensive RCTs.

KW - Efficacy

KW - Entomological parameters

KW - Vector control tool

KW - Vectorial capacity

U2 - 10.1016/j.pt.2014.02.005

DO - 10.1016/j.pt.2014.02.005

M3 - Review article

SN - 1471-4922

VL - 30

SP - 191

EP - 204

JO - Trends In Parasitology

JF - Trends In Parasitology

IS - 4

ER -

Framework for rapid assessment and adoption of new vector control tools

Abstract

Keywords

UN SDGs

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