FLOTAC: A promising technique for detecting helminth eggs in human faeces: A promising technique for detecting helminth eggs in human faeces

Stefanie Knopp, Dominik Glinz, Laura Rinaldi, Khalfan A. Mohammed, Eliézer K. N'Goran, Russell Stothard, Hanspeter Marti, Giuseppe Cringoli, David Rollinson, Jürg Utzinger

Research output: Contribution to journalArticlepeer-review

62 Citations (Scopus)

Abstract

There is a tendency to neglect diagnostic issues in the era of 'preventive chemotherapy' in human helminthiases. However, accurate diagnosis cannot be overemphasized for adequate patient management and monitoring of community-based control programmes. Implicit is a diagnostic dilemma: the more effective interventions are in reducing helminth egg excretion, the less sensitive direct parasitological tests become. Here, experiences gained thus far with the FLOTAC technique for diagnosing common soil-transmitted helminth infections are summarized. A single FLOTAC has higher sensitivity than multiple Kato-Katz thick smears in detecting low-intensity infections. Further validation of the FLOTAC technique in different epidemiological settings is warranted, including diagnosis of intestinal schistosomiasis and food-borne trematodiases.
Original languageEnglish
Pages (from-to)1190-1194
Number of pages5
JournalTransactions of the Royal Society of Tropical Medicine and Hygiene
Volume103
Issue number12
DOIs
Publication statusPublished - 1 Dec 2009
Externally publishedYes

Keywords

  • Ascaris lumbricoides
  • Diagnosis
  • FLOTAC
  • Hookworm
  • Kato-Katz
  • Trichuris trichiura

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