Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

Calman A. MacLennan; Joep J.G. Van Oosterhout; Sarah White; Mark T. Drayson; Eduard E. Zijlstra; Malcolm E. Molyneux

doi:10.1097/qad.0b013e32823bcb03

Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

Calman A. MacLennan
, Joep J.G. Van Oosterhout
, Sarah White
, Mark T. Drayson
, Eduard E. Zijlstra
, Malcolm E. Molyneux

University of Malawi
University of Birmingham
University of Liverpool
Liverpool School of Tropical Medicine

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.

Original language	English
Pages (from-to)	1643-1645
Number of pages	3
Journal	AIDS
Volume	21
Issue number	12
DOIs	https://doi.org/10.1097/qad.0b013e32823bcb03
Publication status	Published - 31 Jul 2007
Externally published	Yes

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SDG 3 Good Health and Well-being

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10.1097/qad.0b013e32823bcb03

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title = "Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests",

abstract = "The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71\% (limits of agreement -2.07 and 3.48\%) for \%CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.",

author = "MacLennan, \{Calman A.\} and \{Van Oosterhout\}, \{Joep J.G.\} and Sarah White and Drayson, \{Mark T.\} and Zijlstra, \{Eduard E.\} and Molyneux, \{Malcolm E.\}",

year = "2007",

month = jul,

day = "31",

doi = "10.1097/qad.0b013e32823bcb03",

language = "English",

volume = "21",

pages = "1643--1645",

journal = "AIDS",

issn = "0269-9370",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

AU - MacLennan, Calman A.

AU - Van Oosterhout, Joep J.G.

AU - White, Sarah

AU - Drayson, Mark T.

AU - Zijlstra, Eduard E.

AU - Molyneux, Malcolm E.

PY - 2007/7/31

Y1 - 2007/7/31

N2 - The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.

AB - The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.

U2 - 10.1097/qad.0b013e32823bcb03

DO - 10.1097/qad.0b013e32823bcb03

M3 - Article

SN - 0269-9370

VL - 21

SP - 1643

EP - 1645

JO - AIDS

JF - AIDS

IS - 12

ER -

Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

Abstract

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