Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

Calman A. MacLennan; Joep J.G. Van Oosterhout; Sarah White; Mark T. Drayson; Eduard E. Zijlstra; Malcolm E. Molyneux

doi:10.1097/qad.0b013e32823bcb03

Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

Calman A. MacLennan, Joep J.G. Van Oosterhout, Sarah White, Mark T. Drayson, Eduard E. Zijlstra, Malcolm E. Molyneux

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Abstract

The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.

Original language	English
Pages (from-to)	1643-1645
Number of pages	3
Journal	AIDS
Volume	21
Issue number	12
DOIs	https://doi.org/10.1097/qad.0b013e32823bcb03
Publication status	Published - 31 Jul 2007
Externally published	Yes

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10.1097/qad.0b013e32823bcb03

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title = "Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests",

abstract = "The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71\% (limits of agreement -2.07 and 3.48\%) for \%CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.",

author = "MacLennan, \{Calman A.\} and \{Van Oosterhout\}, \{Joep J.G.\} and Sarah White and Drayson, \{Mark T.\} and Zijlstra, \{Eduard E.\} and Molyneux, \{Malcolm E.\}",

year = "2007",

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day = "31",

doi = "10.1097/qad.0b013e32823bcb03",

language = "English",

volume = "21",

pages = "1643--1645",

journal = "AIDS",

issn = "0269-9370",

publisher = "Lippincott Williams and Wilkins",

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TY - JOUR

T1 - Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

AU - MacLennan, Calman A.

AU - Van Oosterhout, Joep J.G.

AU - White, Sarah

AU - Drayson, Mark T.

AU - Zijlstra, Eduard E.

AU - Molyneux, Malcolm E.

PY - 2007/7/31

Y1 - 2007/7/31

N2 - The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.

AB - The objective of this study was to investigate the utility of finger-prick blood samples for CD4 cell counting. We estimated agreement between CD4 cell counts in paired finger-prick and venous samples from 110 HIV-infected adults from Malawi. Bias was 6.6 cells/mu l (limits of agreement -50.7 and 63.7 cells/mu l) for absolute counts and 0.71% (limits of agreement -2.07 and 3.48%) for %CD4/lymphocyte suggesting that finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting.

U2 - 10.1097/qad.0b013e32823bcb03

DO - 10.1097/qad.0b013e32823bcb03

M3 - Article

SN - 0269-9370

VL - 21

SP - 1643

EP - 1645

JO - AIDS

JF - AIDS

IS - 12

ER -

Finger-prick blood samples can be used interchangeably with venous samples for CD4 cell counting indicating their potential for use in CD4 rapid tests

Abstract

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