Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial

Grant Theron; Lynn Zijenah; Duncan Chanda; Petra Clowes; Andrea Rachow; Maia Lesosky; Wilbert Bara; Stanley Mungofa; Madhukar Pai; Michael Hoelscher; David Dowdy; Alex Pym; Peter Mwaba; Peter Mason; Jonny Peter; Keertan Dheda

doi:10.1016/s0140-6736(13)62073-5

Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial

Grant Theron
, Lynn Zijenah
, Duncan Chanda
, Petra Clowes
, Andrea Rachow
, Maia Lesosky
, Wilbert Bara
, Stanley Mungofa
, Madhukar Pai
, Michael Hoelscher
, David Dowdy
, Alex Pym
, Peter Mwaba
, Peter Mason
, Jonny Peter
, Keertan Dheda

Division of Pulmonology
University of Zimbabwe
University Teaching Hospital Lusaka
National Institute for Medical Research Tanzania
Ludwig Maximilian University of Munich
German Centre for Infection Research (DZIF)
Harare City Health
McGill University
Johns Hopkins University
South African Medical Research Council
Africa Health Research Institute
Biomedical Research and Training Institute
University of Cape Town

Research output: Contribution to journal › Article › peer-review

390 Citations (Scopus)

Original language	English
Pages (from-to)	424-435
Number of pages	12
Journal	The Lancet
Volume	383
Issue number	9915
DOIs	https://doi.org/10.1016/s0140-6736(13)62073-5
Publication status	Published - 1 Feb 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/s0140-6736(13)62073-5

Cite this

Theron, G., Zijenah, L., Chanda, D., Clowes, P., Rachow, A., Lesosky, M., Bara, W., Mungofa, S., Pai, M., Hoelscher, M., Dowdy, D., Pym, A., Mwaba, P., Mason, P., Peter, J., & Dheda, K. (2014). Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial. The Lancet, 383(9915), 424-435. https://doi.org/10.1016/s0140-6736(13)62073-5

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author = "Grant Theron and Lynn Zijenah and Duncan Chanda and Petra Clowes and Andrea Rachow and Maia Lesosky and Wilbert Bara and Stanley Mungofa and Madhukar Pai and Michael Hoelscher and David Dowdy and Alex Pym and Peter Mwaba and Peter Mason and Jonny Peter and Keertan Dheda",

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Theron, G, Zijenah, L, Chanda, D, Clowes, P, Rachow, A, Lesosky, M, Bara, W, Mungofa, S, Pai, M, Hoelscher, M, Dowdy, D, Pym, A, Mwaba, P, Mason, P, Peter, J & Dheda, K 2014, 'Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial', The Lancet, vol. 383, no. 9915, pp. 424-435. https://doi.org/10.1016/s0140-6736(13)62073-5

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T1 - Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial

AU - Theron, Grant

AU - Zijenah, Lynn

AU - Chanda, Duncan

AU - Clowes, Petra

AU - Rachow, Andrea

AU - Lesosky, Maia

AU - Bara, Wilbert

AU - Mungofa, Stanley

AU - Pai, Madhukar

AU - Hoelscher, Michael

AU - Dowdy, David

AU - Pym, Alex

AU - Mwaba, Peter

AU - Mason, Peter

AU - Peter, Jonny

AU - Dheda, Keertan

PY - 2014/2/1

Y1 - 2014/2/1

U2 - 10.1016/s0140-6736(13)62073-5

DO - 10.1016/s0140-6736(13)62073-5

M3 - Article

SN - 0140-6736

VL - 383

SP - 424

EP - 435

JO - The Lancet

JF - The Lancet

IS - 9915

ER -