Evaluation of the Cepheid® Xpert® C. difficile binary toxin (BT) diagnostic assay

Alan M. McGovern; Grace O. Androga; Peter Moono; Deirdre A. Collins; Niki F. Foster; Barbara J. Chang; Thomas V. Riley

doi:10.1016/j.anaerobe.2018.03.004

Evaluation of the Cepheid^® Xpert^® C. difficile binary toxin (BT) diagnostic assay

Alan M. McGovern
, Grace O. Androga
, Peter Moono
, Deirdre A. Collins
, Niki F. Foster
, Barbara J. Chang
, Thomas V. Riley

University of Western Australia
Queen Elizabeth II Medical Centre Trust
Edith Cowan University
Government of Western Australia, Department of Health
Murdoch University

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

Original language	English
Pages (from-to)	12-16
Number of pages	5
Journal	Anaerobe
Volume	51
DOIs	https://doi.org/10.1016/j.anaerobe.2018.03.004
Publication status	Published - 11 Mar 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Binary toxin
CDT
Clostridium difficile infection
Diagnostics
Piglets

Access to Document

10.1016/j.anaerobe.2018.03.004

Cite this

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title = "Evaluation of the Cepheid{\textregistered} Xpert{\textregistered} C. difficile binary toxin (BT) diagnostic assay",

abstract = "Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92\%) in human and animal faecal samples.",

keywords = "Binary toxin, CDT, Clostridium difficile infection, Diagnostics, Piglets",

author = "McGovern, \{Alan M.\} and Androga, \{Grace O.\} and Peter Moono and Collins, \{Deirdre A.\} and Foster, \{Niki F.\} and Chang, \{Barbara J.\} and Riley, \{Thomas V.\}",

year = "2018",

month = mar,

day = "11",

doi = "10.1016/j.anaerobe.2018.03.004",

language = "English",

volume = "51",

pages = "12--16",

journal = "Anaerobe",

issn = "1075-9964",

publisher = "Academic Press",

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T1 - Evaluation of the Cepheid® Xpert® C. difficile binary toxin (BT) diagnostic assay

AU - McGovern, Alan M.

AU - Androga, Grace O.

AU - Moono, Peter

AU - Collins, Deirdre A.

AU - Foster, Niki F.

AU - Chang, Barbara J.

AU - Riley, Thomas V.

PY - 2018/3/11

Y1 - 2018/3/11

N2 - Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

AB - Strains of Clostridium difficile producing only binary toxin (CDT) are found commonly in animals but not humans. However, human diagnostic tests rarely look for CDT. The Cepheid Xpert C. difficile BT assay detects CDT with equal sensitivity (≥92%) in human and animal faecal samples.

KW - Binary toxin

KW - CDT

KW - Clostridium difficile infection

KW - Diagnostics

KW - Piglets

U2 - 10.1016/j.anaerobe.2018.03.004

DO - 10.1016/j.anaerobe.2018.03.004

M3 - Article

C2 - 29534914

AN - SCOPUS:85045937060

SN - 1075-9964

VL - 51

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ER -