Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

Grace O. Androga; Alan M. McGovern; Briony Elliott; Barbara J. Chang; Timothy T. Perkins; Niki F. Foster; Thomas V. Rileya

doi:10.1128/JCM.03297-14

Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

Grace O. Androga
, Alan M. McGovern
, Briony Elliott
, Barbara J. Chang
, Timothy T. Perkins
, Niki F. Foster
, Thomas V. Rileya

University of Western Australia
Queen Elizabeth II Medical Centre Trust

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

Original language	English
Pages (from-to)	973-975
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	53
Issue number	3
DOIs	https://doi.org/10.1128/JCM.03297-14
Publication status	Published - 1 Mar 2015
Externally published	Yes

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title = "Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains",

abstract = "Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).",

author = "Androga, \{Grace O.\} and McGovern, \{Alan M.\} and Briony Elliott and Chang, \{Barbara J.\} and Perkins, \{Timothy T.\} and Foster, \{Niki F.\} and Rileya, \{Thomas V.\}",

year = "2015",

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doi = "10.1128/JCM.03297-14",

language = "English",

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journal = "Journal of Clinical Microbiology",

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Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains. / Androga, Grace O.; McGovern, Alan M.; Elliott, Briony et al.
In: Journal of Clinical Microbiology, Vol. 53, No. 3, 01.03.2015, p. 973-975.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

AU - Androga, Grace O.

AU - McGovern, Alan M.

AU - Elliott, Briony

AU - Chang, Barbara J.

AU - Perkins, Timothy T.

AU - Foster, Niki F.

AU - Rileya, Thomas V.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

AB - Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

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DO - 10.1128/JCM.03297-14

M3 - Article

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SN - 0095-1137

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JO - Journal of Clinical Microbiology

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IS - 3

ER -

Evaluation of the Cepheid Xpert C. difficile/Epi and Meridian Bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains

Abstract

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