TY - JOUR
T1 - Developing Consensus Standard Operating Procedures (SOPs) to Evaluate New Types of Insecticide-Treated Nets.
AU - Lissenden, Natalie
AU - Armistead, Jennifer S.
AU - Gleave, Katherine
AU - Irish, Seth R.
AU - Martin, Jackline L.
AU - Messenger, Louisa A.
AU - Moore, Sarah J.
AU - Ngufor, Corine
AU - Protopopoff, Natacha
AU - Oxborough, Richard
AU - Spiers, Gus
AU - Lees, Rosemary
PY - 2021/12/21
Y1 - 2021/12/21
N2 - In response to growing concerns over the sustained effectiveness of pyrethroid-only based control tools, new products are being developed and evaluated. Some examples of these are dual-active ingredient (AI) insecticide-treated nets (ITNs) which contain secondary insecticides, or synergist ITNs which contain insecticide synergist, both in combination with a pyrethroid. These net types are often termed 'next-generation' insecticide-treated nets. Several of these new types of ITNs are being evaluated in large-scale randomized control trials (RCTs) and pilot deployment schemes at a country level. However, no methods for measuring the biological durability of the AIs or synergists on these products are currently recommended. In this publication, we describe a pipeline used to collate and interrogate several different methods to produce a singular 'consensus standard operating procedure (SOP)', for monitoring the biological durability of three new types of ITNs: pyrethroid + piperonyl butoxide (PBO), pyrethroid + pyriproxyfen (PPF), and pyrethroid + chlorfenapyr (CFP). This process, convened under the auspices of the Innovation to Impact programme, sought to align methodologies used for conducting durability monitoring activities of next-generation ITNs.
AB - In response to growing concerns over the sustained effectiveness of pyrethroid-only based control tools, new products are being developed and evaluated. Some examples of these are dual-active ingredient (AI) insecticide-treated nets (ITNs) which contain secondary insecticides, or synergist ITNs which contain insecticide synergist, both in combination with a pyrethroid. These net types are often termed 'next-generation' insecticide-treated nets. Several of these new types of ITNs are being evaluated in large-scale randomized control trials (RCTs) and pilot deployment schemes at a country level. However, no methods for measuring the biological durability of the AIs or synergists on these products are currently recommended. In this publication, we describe a pipeline used to collate and interrogate several different methods to produce a singular 'consensus standard operating procedure (SOP)', for monitoring the biological durability of three new types of ITNs: pyrethroid + piperonyl butoxide (PBO), pyrethroid + pyriproxyfen (PPF), and pyrethroid + chlorfenapyr (CFP). This process, convened under the auspices of the Innovation to Impact programme, sought to align methodologies used for conducting durability monitoring activities of next-generation ITNs.
KW - Dual-AI ITN
KW - Durability monitoring
KW - Insecticide resistance management (IRM)
KW - Insecticide-treated net (ITN)
KW - Method validation
KW - PBO ITN
KW - Synergist ITN
U2 - 10.3390/insects13010007
DO - 10.3390/insects13010007
M3 - Article
SN - 2075-4450
VL - 13
SP - 7
JO - Insects
JF - Insects
IS - 1
M1 - 7
ER -