Cytoadherence and virulence - the case of Plasmodium knowlesi malaria.

Farrah A. Fatih; Angela Siner; Atique Ahmed; Lu Chan Woon; Alister Craig; Balbir Singh; Sanjeev Krishna; Janet Cox-Singh

doi:10.1186/1475-2875-11-33

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria.

Farrah A. Fatih
, Angela Siner
, Atique Ahmed
, Lu Chan Woon
, Alister Craig
, Balbir Singh
, Sanjeev Krishna
, Janet Cox-Singh

City St George's, University of London
Universiti Malaysia Sarawak
Hospital Sarikei

Research output: Contribution to journal › Article › peer-review

44 Citations (Scopus)

Abstract

Plasmodium knowlesi infected erythrocytes from human subjects bind in a specific but variable manner to the inducible endothelial receptors ICAM-1 and VCAM. Binding to the constitutively-expressed endothelial receptor CD36 was not detected. Further work will be required to define the pathological consequences of these interactions.

Original language	English
Article number	33
Pages (from-to)	33
Journal	Malaria Journal
Volume	11
DOIs	https://doi.org/10.1186/1475-2875-11-33
Publication status	Published - 3 Feb 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

CD36
Coma
Cytoadherence
ICAM-1
Malaria
P. knowlesi
SICAvar
VCAM

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10.1186/1475-2875-11-33Licence: CC BY

Craig-MalJ-12Final published version, 1.51 MBLicence: CC BY

Cite this

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title = "Cytoadherence and virulence - the case of Plasmodium knowlesi malaria.",

abstract = "Plasmodium knowlesi infected erythrocytes from human subjects bind in a specific but variable manner to the inducible endothelial receptors ICAM-1 and VCAM. Binding to the constitutively-expressed endothelial receptor CD36 was not detected. Further work will be required to define the pathological consequences of these interactions.",

keywords = "CD36, Coma, Cytoadherence, ICAM-1, Malaria, P. knowlesi, SICAvar, VCAM",

author = "Fatih, \{Farrah A.\} and Angela Siner and Atique Ahmed and Woon, \{Lu Chan\} and Alister Craig and Balbir Singh and Sanjeev Krishna and Janet Cox-Singh",

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AU - Fatih, Farrah A.

AU - Siner, Angela

AU - Ahmed, Atique

AU - Woon, Lu Chan

AU - Craig, Alister

AU - Singh, Balbir

AU - Krishna, Sanjeev

AU - Cox-Singh, Janet

PY - 2012/2/3

Y1 - 2012/2/3

N2 - Plasmodium knowlesi infected erythrocytes from human subjects bind in a specific but variable manner to the inducible endothelial receptors ICAM-1 and VCAM. Binding to the constitutively-expressed endothelial receptor CD36 was not detected. Further work will be required to define the pathological consequences of these interactions.

AB - Plasmodium knowlesi infected erythrocytes from human subjects bind in a specific but variable manner to the inducible endothelial receptors ICAM-1 and VCAM. Binding to the constitutively-expressed endothelial receptor CD36 was not detected. Further work will be required to define the pathological consequences of these interactions.

KW - CD36

KW - Coma

KW - Cytoadherence

KW - ICAM-1

KW - Malaria

KW - P. knowlesi

KW - SICAvar

KW - VCAM

U2 - 10.1186/1475-2875-11-33

DO - 10.1186/1475-2875-11-33

M3 - Article

SN - 1475-2875

VL - 11

SP - 33

JO - Malaria Journal

JF - Malaria Journal

M1 - 33

ER -

Cytoadherence and virulence - the case of Plasmodium knowlesi malaria.

Abstract

UN SDGs

Keywords

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