Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature

A. A. Adepoju; A. Akere; G. O. Ogun; B. O. Ogunbosi; A. O. Asinobi; O. Bello; A. E. Orimadegun; Stephen Allen; O. O. Akinyinka

doi:10.1080/20469047.2021.1936393

Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature

A. A. Adepoju, A. Akere, G. O. Ogun, B. O. Ogunbosi, A. O. Asinobi, O. Bello, A. E. Orimadegun, Stephen Allen, O. O. Akinyinka

Clinical Sciences

University of Ibadan

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Sickle cell anaemia (SCA) is a chronic haemolytic anaemia associated with vaso-occlusive painful crises which may affect several systems including the gastro-intestinal system, resulting in abdominal pain. The concurrence of inflammatory bowel disease and haemoglobinopathy is rare. No previously reported concurrent cases of both SCA and ulcerative colitis (UC) in sub-Saharan Africa were found in the literature. A 16-year-old girl with concurrent SCA and UC is presented. She was admitted to University College Hospital, Ibadan with a 1-year history of recurrent peri-umbilical pain and bloody stools. These symptoms were mainly attributed to SCA at the referring hospital, and she was managed for chronic tropical diarrhoea without a remarkable clinical response. This case illustrates the concurrent presentation of SCA and ulcerative colitis which led to the missed and delayed diagnosis of ulcerative colitis.

Original language	English
Pages (from-to)	29-35
Number of pages	7
Journal	Paediatrics and International Child Health
Volume	42
Issue number	1
Early online date	3 Sept 2021
DOIs	https://doi.org/10.1080/20469047.2021.1936393
Publication status	E-pub ahead of print - 3 Sept 2021

Keywords

abdominal pain and bloody stools
colonoscopy
concurrence
Sickle cell anaemia
ulcerative colitis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

Adepoju, A. A., Akere, A., Ogun, G. O., Ogunbosi, B. O., Asinobi, A. O., Bello, O., Orimadegun, A. E., Allen, S., & Akinyinka, O. O. (2021). Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature. Paediatrics and International Child Health, 42(1), 29-35. Advance online publication. https://doi.org/10.1080/20469047.2021.1936393

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abstract = "Sickle cell anaemia (SCA) is a chronic haemolytic anaemia associated with vaso-occlusive painful crises which may affect several systems including the gastro-intestinal system, resulting in abdominal pain. The concurrence of inflammatory bowel disease and haemoglobinopathy is rare. No previously reported concurrent cases of both SCA and ulcerative colitis (UC) in sub-Saharan Africa were found in the literature. A 16-year-old girl with concurrent SCA and UC is presented. She was admitted to University College Hospital, Ibadan with a 1-year history of recurrent peri-umbilical pain and bloody stools. These symptoms were mainly attributed to SCA at the referring hospital, and she was managed for chronic tropical diarrhoea without a remarkable clinical response. This case illustrates the concurrent presentation of SCA and ulcerative colitis which led to the missed and delayed diagnosis of ulcerative colitis.",

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AU - Adepoju, A. A.

AU - Akere, A.

AU - Ogun, G. O.

AU - Ogunbosi, B. O.

AU - Asinobi, A. O.

AU - Bello, O.

AU - Orimadegun, A. E.

AU - Allen, Stephen

AU - Akinyinka, O. O.

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AB - Sickle cell anaemia (SCA) is a chronic haemolytic anaemia associated with vaso-occlusive painful crises which may affect several systems including the gastro-intestinal system, resulting in abdominal pain. The concurrence of inflammatory bowel disease and haemoglobinopathy is rare. No previously reported concurrent cases of both SCA and ulcerative colitis (UC) in sub-Saharan Africa were found in the literature. A 16-year-old girl with concurrent SCA and UC is presented. She was admitted to University College Hospital, Ibadan with a 1-year history of recurrent peri-umbilical pain and bloody stools. These symptoms were mainly attributed to SCA at the referring hospital, and she was managed for chronic tropical diarrhoea without a remarkable clinical response. This case illustrates the concurrent presentation of SCA and ulcerative colitis which led to the missed and delayed diagnosis of ulcerative colitis.

KW - abdominal pain and bloody stools

KW - colonoscopy

KW - concurrence

KW - Sickle cell anaemia

KW - ulcerative colitis

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DO - 10.1080/20469047.2021.1936393

M3 - Article

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JF - Paediatrics and International Child Health

IS - 1

ER -

Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature

Abstract

Keywords

UN SDGs

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