Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.

Rafael V. Veiga; Sergio S. Cunha; Vitor C. C. Dattoli; Álvaro C. Cruz; Philip Cooper; Laura C. Rodrigues; Maurício L. Barreto; Neuza M. Alcantara-Neves

doi:10.1186/1471-2466-11-24

Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.

Rafael V. Veiga
, Sergio S. Cunha
, Vitor C. C. Dattoli
, Álvaro C. Cruz
, Philip Cooper
, Laura C. Rodrigues
, Maurício L. Barreto
, Neuza M. Alcantara-Neves

Liverpool School of Tropical Medicine

Liverpool School of Tropical Medicine

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

These data do not support previous data showing a protective effect of HAV against atopy, but did show inverse associations between SPT+ (but not specific IgE+) and infections with HSV and EBV. These findings suggest that different viral infections may protect against SPT+ in different settings and may indicate an immunoregulatory role of such infections on immediate hypersensitivity responses. The data provide no support for a protective effect of viral infections against asthma in this population.

Original language	English
Article number	24
Journal	BMC Pulmonary Medicine
Volume	11
DOIs	https://doi.org/10.1186/1471-2466-11-24
Publication status	Published - 14 May 2011

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title = "Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.",

abstract = "These data do not support previous data showing a protective effect of HAV against atopy, but did show inverse associations between SPT+ (but not specific IgE+) and infections with HSV and EBV. These findings suggest that different viral infections may protect against SPT+ in different settings and may indicate an immunoregulatory role of such infections on immediate hypersensitivity responses. The data provide no support for a protective effect of viral infections against asthma in this population.",

author = "Veiga, \{Rafael V.\} and Cunha, \{Sergio S.\} and Dattoli, \{Vitor C. C.\} and Cruz, \{{\'A}lvaro C.\} and Philip Cooper and Rodrigues, \{Laura C.\} and Barreto, \{Maur{\'i}cio L.\} and Alcantara-Neves, \{Neuza M.\}",

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AU - Veiga, Rafael V.

AU - Cunha, Sergio S.

AU - Dattoli, Vitor C. C.

AU - Cruz, Álvaro C.

AU - Cooper, Philip

AU - Rodrigues, Laura C.

AU - Barreto, Maurício L.

AU - Alcantara-Neves, Neuza M.

PY - 2011/5/14

Y1 - 2011/5/14

N2 - These data do not support previous data showing a protective effect of HAV against atopy, but did show inverse associations between SPT+ (but not specific IgE+) and infections with HSV and EBV. These findings suggest that different viral infections may protect against SPT+ in different settings and may indicate an immunoregulatory role of such infections on immediate hypersensitivity responses. The data provide no support for a protective effect of viral infections against asthma in this population.

AB - These data do not support previous data showing a protective effect of HAV against atopy, but did show inverse associations between SPT+ (but not specific IgE+) and infections with HSV and EBV. These findings suggest that different viral infections may protect against SPT+ in different settings and may indicate an immunoregulatory role of such infections on immediate hypersensitivity responses. The data provide no support for a protective effect of viral infections against asthma in this population.

U2 - 10.1186/1471-2466-11-24

DO - 10.1186/1471-2466-11-24

M3 - Article

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VL - 11

JO - BMC Pulmonary Medicine

JF - BMC Pulmonary Medicine

M1 - 24

ER -

Chronic virus infections supress atopy but not asthma in a set of children from a large Latin American city: a cross-section study.

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