Chapter 9: The Comet Assay: Clinical Applications

M. M. Piperakis, Nadia Kontogianni, S. M. Piperakis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

The single-cell gel electrophoresis (SCGE) or Comet assay is a technique widely employed in environmental and radiation toxicology as well as in cancer research with the aim of assessing DNA damage and repair by measuring DNA strand breaks. In the present review we outline the clinical applications of the Comet assay. In particular, we aim to highlight the importance of the technique in clinical medicine.
Original languageEnglish
Title of host publicationIssues in Toxicology
EditorsDiana Anderson, Alok Dhawan
Pages195-237
Number of pages43
Edition30
ISBN (Electronic)978-1-78262-915-3
DOIs
Publication statusPublished - 1 Jan 2017

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