Chapter 9: The Comet Assay: Clinical Applications

M. M. Piperakis; Nadia Kontogianni; S. M. Piperakis

doi:10.1039/9781782622895-00193

Chapter 9: The Comet Assay: Clinical Applications

M. M. Piperakis
, Nadia Kontogianni
, S. M. Piperakis

Clinical Sciences

John Innes Centre
University of Thessaly

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The single-cell gel electrophoresis (SCGE) or Comet assay is a technique widely employed in environmental and radiation toxicology as well as in cancer research with the aim of assessing DNA damage and repair by measuring DNA strand breaks. In the present review we outline the clinical applications of the Comet assay. In particular, we aim to highlight the importance of the technique in clinical medicine.

Original language	English
Title of host publication	Issues in Toxicology
Editors	Diana Anderson, Alok Dhawan
Pages	195-237
Number of pages	43
Edition	30
ISBN (Electronic)	978-1-78262-915-3
DOIs	https://doi.org/10.1039/9781782622895-00193
Publication status	Published - 1 Jan 2017

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10.1039/9781782622895-00193

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Chapter 9: The Comet Assay: Clinical Applications

Abstract

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